Results 71 to 80 of about 366,832 (262)
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Illness: An Opportunity for Spiritual Growth
Spirituality is an innate aspect of being human, and every patient has the potential for spiritual growth through suffering from an illness. However, spirituality and spiritual care are rarely mentioned in the field of medicine, either because their definition can be ambiguous or because their nature can be highly personal.
openaire +2 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Changing trends in the global economy have reshaped industrial relations due to transformation in the workforce composition, resulting in compulsion on companies to audit their organizational climate, HR practices, process, system, and style of managing ...
Panicker, A., Sharma, A.
doaj
The Relationship between Accounting Variables and Stock Price Movements in Tehran Stock Exchange (TSE) [PDF]
This study investigated the relationship between accounting Variable and stock price movements. I study earnings yield, capital investment, changes in profitability and growth opportunities, as a cash flow related factors, and discount rates that based ...
Omid Pourheydari
doaj
Economic Growth and Poverty: The Mediating Effect of Employment
The results of previous research on the relationship between economic growth and poverty have shown inconclusive results. This could be due to the fact that the relationship between these variables is indirect.
Sodik Dwi Purnomo, Istiqomah Istiqomah
doaj +1 more source
Early‐Phase Research in Pediatric Neuro‐Oncology
Pediatric Blood &Cancer, EarlyView.
Jonathan Cunningham
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source

