Results 51 to 60 of about 6,998,872 (229)
The impact of short-term debt on accruals-based earnings management – evidence from Vietnam
Cogent Economics & Finance, 2020 This study seeks to examine the relationship between short-term debt maturity and accruals-based earnings management using a sample of listed firms in Vietnam from 2010–2017.
Trinh Quoc Trung +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Long-term Debts and Overinvestment in Cash and Capital Expenditures: An Agency Perspective [PDF]
مطالعات تجربی حسابداری مالی, 2012 Managers' tendency to overinvestment is one of the agency costs that due to conflict of Interests between managements and shareholders the firms are encountered with.
Javad MOradi, Ahmad Rahmanian
doaj
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Jurnal Riset Manajemen Sains Indonesia, 2015 This study is conducted to see the effect of the company's firm size, growth opportunities, leverage and liquidity on the decision of hedging with foreign currency derivative instruments on manufacturing companies listed on the Indonesian Stock Exchange (
Gatot Nazir Ahmad +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Fintechs in South Africa: Impact on regulation, incumbents and consumers
South African Journal of Information ManagementBackground: The financial services industry in South Africa has undergone many changes that have given birth to fintechs. Most of these changes are driven by the advent of technology and evolving customer expectations.
Simphiwe K. Cele, Nhlanhla W. Mlitwa
doaj +1 more source
The effect of the characteristics of the internal governance mechanisms on the growth opportunities: The Tunisian evidence [PDF]
Contabilitate şi Informatică de GestiuneResearch Question: Do the characteristics of the board of directors and the characteristics of audit committee influence Tunisian companies’ growth opportunities?
Raida Chakroun
doaj +1 more source