Results 111 to 120 of about 3,975,986 (304)

Determination of Temperature Dependent Growth Parameters in Psychrotrophic Pathogen Bacteria and Tentative Use of Mean Kinetic Temperature for the Microbiological Control of Food

open access: yesFrontiers in Microbiology, 2018
Temperature is the main factor to control the microbial growth in perishable foods. The psychrotrophic pathogen bacteria are microorganisms of concern for food products with extended shelf life in chilling conditions.
Andrea De Silvestri   +4 more
doaj   +1 more source

Classification of Biodegradability by Growth Kinetic Parameters

open access: yesEcotoxicology and Environmental Safety, 1994
On the basis of classical Monod equations for microbial growth, kinetic parameter values are assessed to enable the characterization of biodegradability as a substance property. Although growth is a microbial property, the substance selects those species from a mixed inoculum that can profit at most under the prevailing conditions.
openaire   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

A cellular automata modelling of dendritic crystal growth based on Moore and von Neumann neighbourhood [PDF]

open access: yes, 2008
An important step in understanding crystal growth patterns involves simulation of the growth processes using mathematical models. In this paper some commonly used models in this area are reviewed, and a new simulation model of dendritic crystal growth ...
Billings, S.A., Coca, D., Zhao, Y.
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

From organism to population: the role of life-history theory [PDF]

open access: yes, 1994
The role of life-history theory in population and evolutionary analyses is outlined. In both cases general life histories can be analysed, but simpler life histories need fewer parameters for their description.
Sibly, R.M.
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Effects of the interaction between tank color and type of feed pellets on biological and physiological indicators in red hybrid tilapia (Oreochromis mossambicus × Oreochromis niloticus) juveniles reared in brackish water

open access: yesJournal of the World Aquaculture Society
The present work aimed to investigate the impacts of tank color (transparent, light blue, and red), feed pellet types (floating and sinking), and their interaction on the performance and welfare of red hybrid tilapia juveniles with an initial average ...
Ashraf Y. El‐Dakar   +8 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

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