Results 181 to 190 of about 1,461,056 (318)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Pituitary Neuroendocrine Tumors Extending Primarily Below the Sella and into the Clivus: A Distinct Growth Pattern with Specific Challenges. [PDF]

Curr Oncol
Sannwald LW, Kreße N, Grübel N, Knoll A, Roßkopf J, Hlavac M, Wirtz CR, Pala A.   +7 more
europepmc   +1 more source

Investigating the Relationship between the Dimensions and Morphology of Sella Turcica with the Long-Face Growth Pattern and the Vertical Growth Pattern. [PDF]

Int J Dent, 2023
Nabavizadeh A, Zeini N, Azarm A, Khalili P, Hajipour F, Khaghani S.   +5 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

The colorectal liver metastasis growth pattern phenotype is not dependent on genotype. [PDF]

Br J Cancer
Höppener DJ, Verheul SML, Nierop PMH, Buisman FE, Galjart B, Wilting SM, Pugh SA, Richman SD, Balachandran VP, Jarnagin WR, Kingham TP, Vermeulen PB, Shia J, Quirke P, Bridgewater JA, Maughan TS, Groot Koerkamp B, Grünhagen DJ, Verhoef C, Primrose JN, D'Angelica MI, S:CORT consortium.   +21 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Influence of vertical growth pattern on masseter muscle morphology: evidence from cephalometric and ultrasound assessment in eighteen growing subjects. [PDF]

Front Dent Med
Dipalma G, Inchingolo AD, Guglielmo M, Di Venere D, Inchingolo F, Palermo A, Marinelli G, Inchingolo AM.   +7 more
europepmc   +1 more source

Growth Patterns

Offset, 1969
openaire   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Plant nutation relies on steady propagation of spatially asymmetric growth pattern. [PDF]

Quant Plant Biol
Rivière M, Peaucelle A, Derr J, Douady S.   +3 more
europepmc   +1 more source