Results 91 to 100 of about 1,094,026 (268)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Effects of different feeding strategies for the frozen Antarctic krill meal on growth, muscle nutrition, digestive enzyme activity, immunity, molting, and gut microbiota structure of Cherax quadricarinatus

Frontiers in Marine Science
To investigate the effect of the frozen Antarctic krill meal (AKM) as an nutritional supplement in Cherax quadracarinatus culturing, an experiment was designed with the following groups: a control group (C) fed with basic feed throughout the experiment ...
Zhuang Mai, Zhuang Mai, Jie Wei, Yakun Wang, Zhongqiang Zeng, Fubai Liu, Fubai Liu, Huarong Li, Huarong Li, Qiyao Su, Qiyao Su, Kunhao Hong, Kunhao Hong, Qiaoyan Zhou, Tianhui Jiao, Tianhui Jiao, Tianyan Yang, Lingyun Yu   +17 more
doaj   +1 more source

Performance and Growth of the Eurozone Export

Procedia Economics and Finance, 2014
AbstractThe paper is focused on the performance and growth of the Eurozone export in the period of 1999–2012. The results of the empirical analysis show an increase of the export performance in the 12 euro area countries measured as export divided by gross domestic product and an increase of the export performance in all 17 countries of the euro area ...
openaire   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Effect of Standardized Ginger (Zingiber officinale Roscoe) Extract on Gut Morphology, Microbiota Composition, and Growth Performance in Broiler Chickens

Agriculture
With increasing concerns over antibiotic resistance in livestock, there is an urgent need for sustainable alternatives to enhance health and productivity in poultry production. Ginger (Zingiber officinale Roscoe), a phytobiotic recognized for its diverse
Martina Đurić Jarić, Željko Gottstein, Silvijo Vince, Ivona Žura Žaja, Maksimiljan Brus, Dražen Đuričić, Marko Samardžija, Hrvoje Valpotić   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Nutritional status and compensatory growth in yak calves maintained on different plane of nutrition

Indian Journal of Animal Sciences, 2023
D MEDHI, P CHAKRAVARTY, S DEORI, A SANTRA   +3 more
doaj   +1 more source

Effects of Soybean Meal Fermented by Lactobacillus plantarum NX69 on Growth Performance and Intestinal Health of Nursery Pigs

Fermentation
The Intestinal system of nursery pigs is not fully matured and is easily disturbed by dietary composition and nutritional content. Probiotic-fermented feed has emerged as a beneficial dietary form for nursery pigs and is widely utilized in the livestock ...
Mengshi Zhao, Fengqiang Lin, Song Peng, Yaxiong Ma, Huini Wu, Zhaolong Li   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source