Results 211 to 220 of about 8,209,592 (350)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

<i>Bacillus velezensis</i> CNPMS-22 as biocontrol agent of pathogenic fungi and plant growth promoter. [PDF]

Front Microbiol
Figueiredo JEF, Diniz GFD, Marins MS, Silva FC, Ribeiro VP, Lanza FE, de Oliveira-Paiva CA, Cruz-Magalhães V.   +7 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Comparative assessment of growth performance and meat quality in Water Hyacinth and antibiotic (growth promoter) supplemented broilers. [PDF]

Poult Sci
Mustari A, Haque MI, Rashid S, Khan MS, Alam M, Miah MA, Azad MAK, Chowdhury EH.   +7 more
europepmc   +1 more source

Author Correction: Entomopathogenic fungi Beauveria bassiana and Metarhizium anisopliae play roles of maize (Zea mays) growth promoter. [PDF]

Sci Rep, 2022
Liu Y, Yang Y, Wang B.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

The Use of Coffee Cherry Pulp Extract as an Alternative to an Antibiotic Growth Promoter in Broiler Diets. [PDF]

Animals (Basel)
Tapingkae W, Srinual P, Khamtavee P, Pintalerd N, Chaiyaso T, Yachai M, Kanmanee C, Lumsangkul C, Srinual O.   +8 more
europepmc   +1 more source

Calliterpenone, a natural plant growth promoter from a medicinal plant Callicarpa macrophylla, sustainably enhances the yield and productivity of crops. [PDF]

Front Plant Sci, 2022
Pandey P, Pandey SS, Awasthi A, Tripathi A, Singh HP, Singh AK, Tandon S, Kalra A.   +7 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Harnessing natural feed additives for sustainable production and economics: the role of <i>Thymus vulgaris</i> L. oil as an antimicrobial agent and a growth promoter in improving production and health of broiler chickens. [PDF]

Front Immunol
Saied AM, Attia AI, Reda FM, El-Kholy MS, Al-Badwi MA, Azzam M, Di Cerbo A, Alagawany M, El-Tarabily KA, El Nagar AG.   +9 more
europepmc   +1 more source