Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Potency of <i>Lacticaseibacillus paracasei</i> as an alternative to antibiotic growth promoter in broiler chicken challenged with avian pathogenic <i>Escherichia coli</i>. [PDF]
Lokapirnasari WP +12 more
europepmc +1 more source
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Indigenous fungi from corn as a potential plant growth promoter and its role in Fusarium verticillioides suppression on corn. [PDF]
Mirsam H +9 more
europepmc +1 more source
Foxc1 regulates Pecam-1 Expression in embryonic Endothelial Progenitor Cells [PDF]
Lamparter, Mathias
core
Insights into a long life without cancer: The case of the bowhead whale
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
Checkpoint blockade and the stem‐like T cell trade‐off
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley +1 more source
Effects of antibiotic growth promoter and its natural alternative on poultry cecum ecosystem: an integrated analysis of gut microbiota and host expression. [PDF]
Peng C, Ghanbari M, May A, Abeel T.
europepmc +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Comparative genomics reveals insights into the potential of Lysinibacillus irui as a plant growth promoter. [PDF]
Hilário S +6 more
europepmc +1 more source

