Results 91 to 100 of about 15,748,264 (316)

The effects of stochasticity at the single-cell level and cell size control on the population growth [PDF]

open access: yesarXiv, 2016
Establishing a quantitative connection between the population growth rate and the generation times of single cells is a prerequisite for understanding evolutionary dynamics of microbes. However, existing theories fail to account for the experimentally observed correlations between mother-daughter generation times that are unavoidable when cell size is ...
arxiv  

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

open access: yesFEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek   +15 more
wiley   +1 more source

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

open access: yesFEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner   +7 more
wiley   +1 more source

The Association of Cell Division Regulated by DicC With the Formation of Viable but Non-culturable Escherichia coli O157:H7

open access: yesFrontiers in Microbiology, 2019
The viable but non-culturable (VBNC) state, in which bacteria fail to grow on routine culture media but are actually alive, has been widely recognized as a strategy adopted by bacteria to cope with stressful environments.
Hanxu Pan   +10 more
doaj   +1 more source

Growth window and possible mechanism of millimeter-thick single-walled carbon nanotube forests [PDF]

open access: yesarXiv, 2007
Our group recently reproduced the water-assisted growth method, so-called "super growth", of millimeter-thick single-walled carbon nanotube (SWNT) forests by using C2H4/ H2/ H2O/ Ar reactant gas and Fe/ Al2O3 catalyst. In this current work, a parametric study was carried out on both reaction and catalyst conditions.
arxiv  

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Growth and biomass allocation of the C4 grasses Brachiaria brizantha and B. humidicola under shade Crescimento e alocação de biomassa nas gramíneas C4 Brachiaria brizantha e B. humidicola sob sombreamento

open access: yesPesquisa Agropecuária Brasileira, 2000
The growth and biomass allocation responses of the tropical forage grasses Brachiaria brizantha cv. Marandu and B. humidicola were compared for plants grown outdoors, in pots, in full sunlight and those shaded to 30% of full sunlight over a 30day period.
MOACYR BERNARDINO DIAS-FILHO
doaj   +1 more source

On growth rate and contact homology [PDF]

open access: yesAlgebraic & Geometric Topology, 2015
It is a conjecture of Colin and Honda that the number of Reeb periodic orbits of universally tight contact structures on hyperbolic manifolds grows exponentially with the period, and they speculate further that the growth rate of contact homology is polynomial on non-hyperbolic geometries.
openaire   +4 more sources

Growth rate regulation in Escherichia coli.

open access: yesFEMS Microbiology Reviews, 2012
Growth rate regulation in bacteria has been an important issue in bacterial physiology for the past 50 years. This review, using Escherichia coli as a paradigm, summarizes the mechanisms for the regulation of rRNA synthesis in the context of systems ...
D. Jin, C. Cagliero, Y. Zhou
semanticscholar   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

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