Results 141 to 150 of about 5,909,239 (281)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Direct Analysis in Real-Time Tandem Mass Spectrometry for Rapid Screening of Thirty-one Plant Growth Regulator Residues in Rehmannia glutinosa. [PDF]

J Am Soc Mass Spectrom
E R, Shang S, Tian J, Sun J, Li X, Yao W, Feng Y.   +6 more
europepmc   +1 more source

Regulating hair growth [PDF]

Nature Immunology, 2017
openaire   +2 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Effects of plant growth regulator treatments on quality-related traits and the establishment of cultivar-specific cultivation conditions in small- and medium-sized lily bulbs. [PDF]

Front Plant Sci
Jeon KE, Hyeon HG, Heo S.
europepmc   +1 more source

Exogenous plant growth regulator and foliar fertilizers for phytoextraction of cadmium with Boehmeria nivea [L.] Gaudich from contaminated field soil. [PDF]

Sci Rep, 2023
Peng W, He Y, He S, Luo J, Zeng Y, Zhang X, Huo Y, Jie Y, Xing H.   +8 more
europepmc   +1 more source

Bone biodynamics in orthodontic and orthopedic treatment

, 1992
http://babel.hathitrust.org/cgi/pt?id=mdp.39015024931506;view=2up;ui=fullscreen#page/n0/mode ...
Symposium on Craniofacial Growth
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Multi-level assessment of chronic toxicity of the insect growth regulator lufenuron in the non-target aquatic organism Daphnia magna. [PDF]

Environ Geochem Health
Dane H, Aksakal Ö, Şişman T, Gür C, Alat Ö.   +4 more
europepmc   +1 more source

A Potential Lead for Insect Growth Regulator: Design, Synthesis, and Biological Activity Evaluation of Novel Hexacyclic Pyrazolamide Derivatives. [PDF]

Molecules, 2023
Guo B, Jiang B, Wang C, Jin X, Wang L, Yang Z, Luo S, Yang Q, Zhang L, Yang X.   +9 more
europepmc   +1 more source