Results 101 to 110 of about 1,188,871 (312)

Productivity growth in electric energy retail in Colombia. A bootstrapped malmquist indices approach [PDF]

This paper offers a productivity growth estimate for electric energy commercialization firms in Colombia, using a non-parametric Malmquist bootstrap methodology. The estimation and methodology serve two main purposes. First, in Colombia commercialization
Julieth Santamaría, Rodrigo Taborda
core  

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

The miR164e–NAC32 module orchestrates maize plant height via post-translational regulation of DELLA protein stability

Plant Communications
Optimization of plant architecture requires precise regulation of internode elongation; however, the post-translational mechanisms that integrate microRNA and phytohormone signaling remain poorly understood. Here, we describe a hierarchical miR164e–NAC32–
Chuanxi Peng, Xi Zhao, Jinzhong Xiao, Xingyu Zhong, Limei Chen, Yan He, Zhaohu Li, Yuyi Zhou, Liusheng Duan   +8 more
doaj   +1 more source

Effects of tank mixes of MON 3539 and selected compounds in RoundupReady Flex® cotton – 2005 [PDF]

, 2006
Field experiments were conducted in 2005 to evaluate potential weed control interactions when MON 3539 (glyphosate) was applied with several insecticides and a plant growth regulator to RoundupReady Flex® cotton.
Colwell, Kyle, Hardke, Jarrod, Lorenz, Gus, Shelton, Craig   +3 more
core   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Leaf ethylene and auxin act as core factors in the regulation of temperature on thidiazuron-induced cotton defoliation

Industrial Crops and Products
The defoliant thidiazuron is applied worldwide to enhance the fiber quality of machine-harvested cotton, and its efficiency is profoundly regulated by temperature. However, little is known about how the temperature after defoliant application affects the
Keke Yu, Zhenwang Zhang, Zexin Wei, Kexin Li, Xiyu Jia, Mingfeng Yang, Jianxin Dong, Mingwei Du, Xiaoli Tian, Zhaohu Li   +9 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Regulating sink-source ratio optimizes cotton defoliation efficiency during the early-to-mid flowering and boll stages

Industrial Crops and Products
The sink-source relationship significantly influences chemical defoliation in cotton. However, studies on the effects of sink-source manipulations at different phenological stages remain limited.
Zhenwang Zhang, Kexin Li, Jiaqi Zhang, Qinghua Liao, Yukun Wang, Xiaocheng Yuan, Keke Yu, Mingfeng Yang, Guodong Chen, Sumei Wan, Shanwei Lou, Fangjun Li, Mingwei Du, Xiaoli Tian, Zhaohu Li   +14 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source