Plant Growth Regulator- and Elicitor-Mediated Enhancement of Biomass and Andrographolide Production of Shoot Tip-Culture-Derived Plantlets of Andrographis paniculata (Burm.f.) Wall. (Hempedu Bumi). [PDF]
Patuhai A +5 more
europepmc +1 more source
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Sublethal Effects of the Insect Growth Regulator Novaluron on the Midgut Integrity and Survival of Adult Honey Bee <i>Apis mellifera</i> Workers. [PDF]
Soares de Oliveira M +7 more
europepmc +1 more source
Susceptibility status of major malaria vectors to novaluron, an insect growth regulator South-Eastern Tanzania. [PDF]
Ngonzi AJ +5 more
europepmc +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Sex-specific difference on anxiety- and depressive-like behavior in neuronal growth regulator 1-knockout mice. [PDF]
Lee SR +7 more
europepmc +1 more source
Neuronal growth regulator 1 promotes adipocyte lipid trafficking via interaction with CD36. [PDF]
Yoo A, Joo Y, Cheon Y, Lee SJ, Lee S.
europepmc +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Co-expression of growth regulator genes HvWUS and HvBBM2 enhances barley transformation efficiency. [PDF]
He X +7 more
europepmc +1 more source

