Results 71 to 80 of about 1,679,385 (265)
How to quickly monitor the growth process of maize on a large scale is crucial for regional maize growth assessment, yield estimation, and farmland management.
Huichun Ye +12 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
A aplicação repetida de bensulfurão-metilo em arrozais dos vales dos rios Sorraia, Sado e Mondego seleccionaram populações resistentes (R) de Alisma plantago-aquatica (Mo260, Sa88, So306 e So307). Determinou-se o nível de resistência (NR= ED50 R/ ED50 S)
Isabel M. Calha +2 more
doaj
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Transcriptome sequencing was performed to analyse the differentially expressed genes (DEGs) of skeletal muscle in Fujian white rabbits at different stages, to help establish gene expression datasets for further investigation of the mechanisms underlying ...
DongJin Chen +7 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
AbstractStages of growth models are important for understanding scale-ups. One of the differences between scale-ups and HGFs is that research on HGFs does not take growth stages into account, as long as growth is fast enough. This chapter presents Steve Blank’s 4-stage model of firm growth, where scaling up is stage 3.
Alex Coad +3 more
openaire +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Snap Bean (Phaseolus vulgaris L.) Response to Postemergence Herbicides at Different Growth Stages
Weeds competing with snap beans can reduce harvest efficiency and lower yields. Postemergence herbicides are most effective when applied to small weed seedlings, but their application timing must also account for crop development to avoid injury ...
Lynn Sosnoskie +3 more
doaj +1 more source

