Results 71 to 80 of about 1,679,385 (265)

Extraction of maize growth stages in the Sanjiang Plain of China from 2003 to 2022 and their spatio-temporal changes in response to meteorological variables

open access: yesFrontiers in Plant Science
How to quickly monitor the growth process of maize on a large scale is crucial for regional maize growth assessment, yield estimation, and farmland management.
Huichun Ye   +12 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Resistências cruzadas em biótipos de Alisma Plantago-Aquatica resistentes ao bensulfurão-metilo e suas consequências Cross resistance in bensulfuron-methyl resistant Alisma Plantago-Aquatica biotypes

open access: yesRevista de Ciências Agrárias, 2008
A aplicação repetida de bensulfurão-metilo em arrozais dos vales dos rios Sorraia, Sado e Mondego seleccionaram populações resistentes (R) de Alisma plantago-aquatica (Mo260, Sa88, So306 e So307). Determinou-se o nível de resistência (NR= ED50 R/ ED50 S)
Isabel M. Calha   +2 more
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Comparative transcriptome and histomorphology analysis of skeletal muscle in Fujian white rabbit (Oryctolagus cuniculus) at different growth stages

open access: yesWorld Rabbit Science
Transcriptome sequencing was performed to analyse the differentially expressed genes (DEGs) of skeletal muscle in Fujian white rabbits at different stages, to help establish gene expression datasets for further investigation of the mechanisms underlying ...
DongJin Chen   +7 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Stages of Growth Models

open access: yes
AbstractStages of growth models are important for understanding scale-ups. One of the differences between scale-ups and HGFs is that research on HGFs does not take growth stages into account, as long as growth is fast enough. This chapter presents Steve Blank’s 4-stage model of firm growth, where scaling up is stage 3.
Alex Coad   +3 more
openaire   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Snap Bean (Phaseolus vulgaris L.) Response to Postemergence Herbicides at Different Growth Stages

open access: yesHortTechnology
Weeds competing with snap beans can reduce harvest efficiency and lower yields. Postemergence herbicides are most effective when applied to small weed seedlings, but their application timing must also account for crop development to avoid injury ...
Lynn Sosnoskie   +3 more
doaj   +1 more source

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