Results 91 to 100 of about 9,491,957 (283)

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Snap Bean (Phaseolus vulgaris L.) Response to Postemergence Herbicides at Different Growth Stages

open access: yesHortTechnology
Weeds competing with snap beans can reduce harvest efficiency and lower yields. Postemergence herbicides are most effective when applied to small weed seedlings, but their application timing must also account for crop development to avoid injury ...
Lynn Sosnoskie   +3 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Change of Fresh Yield and Agro-Morphological Traits of Pisum sativum L. Under Color Commercial Shading Nets in Different Intensities

open access: yesAgriculture
Different coloured and intensity commercial shade nets are increasingly proposed as a low-cost tool for mitigating abiotic stress in semi-arid cropping systems, but cultivar-specific responses in grain legumes remain poorly documented.
Sibel İpekeşen   +7 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Industrial Hemp Response to Waterlogging Stress: Influence of Duration and Growth Stage on Physiological Performance and Yield

open access: yesCrops
Industrial hemp is often considered sensitive to waterlogging; however, empirical evidence remains scarce. This study evaluated the effects of waterlogging duration and timing on the physiology, growth, and development of hemp under controlled conditions.
Induni Vijaya Kumar   +3 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Spectral-temporal characterization of wheat cultivars through NDVI obtained by terrestrial sensors

open access: yesRevista Brasileira de Engenharia Agrícola e Ambiental
Remote sensing applications in agriculture are presented as a very promising reality, but research is still needed for the correct use of spectral data. The objective of this study was to evaluate the spectral-temporal patterns of eleven wheat cultivars (
Carlos E. V. Cattani   +5 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

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