Results 41 to 50 of about 258,980 (301)

Classification and hydrocarbon distribution of passive continental margin basins

Petroleum Exploration and Development, 2016
Sixty-six passive continental margin basins around the world were compared comprehensively from the aspect of seismogeology on the basis of plate tectonics.
Zhixin WEN, Hong XU, Zhaoming WANG, Zhengjun HE, Chengpeng SONG, Xi CHEN, Yonghua WANG   +6 more
doaj   +1 more source

Ethnic Differences in the Association Between SOD2 rs4880 and Hepatotoxicity in Pediatric Acute Lymphoblastic Leukemia: A Report From the REDIAL Consortium

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Treatment‐associated hepatotoxicity (TAH) is a common complication of pediatric acute lymphoblastic leukemia (ALL) treatment, but genetic risk factors remain poorly understood. We evaluated the SOD2 rs4880 variant in 544 children with ALL at Texas Children's Hospital. After adjusting for demographic and clinical covariates, the rs4880 C allele
Emily J. Mason, John P. Woodhouse, Joanna S. Yi, M. Monica Gramatges, Olga A. Taylor, Veronica A. Morales, Shalini Dhamodharan, Marley Roberts, Karen R. Rabin, Philip J. Lupo, Michael E. Scheurer, Van Huynh, Steven D. Mittelman, Etan Orgel, Austin L. Brown   +14 more
wiley   +1 more source

Timing of the initiation and duration of the Cretaceous extensional regime in South‐east China: Constraints from growth strata in terrigenous basins

The Depositional Record
There has been no consensus yet regarding the precise initial timing and duration of the late Mesozoic extensional tectonics in the South‐eastern China Block.
Xinqi Yu, Jun Hu, Wei Li, Kun Liu, Ran Hao   +4 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Microclimatic conditions in the canopy strata and its relations with the soybean yield

Anais da Academia Brasileira de Ciências
: Despite its economic importance, the microclimate in soybean canopies has not yet been studied in detail. Such a study can yield valuable information regarding the interaction of a crop with its environment.
FELIPE SCHWERZ, BRAULIO O. CARON, ELVIS F. ELLI, JOHN R. STOLZLE, SANDRO L.P. MEDEIROS, JAQUELINE SGARBOSSA, ANA P. ROCKENBACH   +6 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

The geometry of growth strata as evidence for the evolution of the Nahreh anticline, the interior Fars region [PDF]

علوم زمین خوارزمی
The study area is located in the northern margin of the Fars paleo high plateau in the Zagros fold-thrust belt. The presence of growth strata in the young Aghajari and Bakhtiari formations shows the continuation of folding until the Pliocene and ...
Zahra Tavazo, Ebrahim Gholami, Hossein Motamedi, Bahman soleimany, Jameh Vergés   +4 more
doaj  

Reconciling patterns of long-term topographic growth with coseismic uplift by synchronous duplex thrusting

Nature Communications, 2023
How long-term changes in surface topography relate to coseismic uplift is key to understanding the creation of high elevations along active mountain fronts, and remains hotly debated.
Yuqing Zhang, Hanlin Chen, Xuhua Shi, Rafael Almeida, Richard Walker, Xiubin Lin, Xiaogan Cheng, Hongdan Deng, Zhuxin Chen, Xiu Hu   +9 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source