Results 71 to 80 of about 258,980 (301)
The singular set of mean curvature flow with generic singularities [PDF]
, 2015 A mean curvature flow starting from a closed embedded hypersurface in $R^{n+1}$ must develop singularities. We show that if the flow has only generic singularities, then the space-time singular set is contained in finitely many compact embedded $(n-1 ...
Colding, Tobias Holck +1 more
core +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Stability of roof structure and its control in steeply inclined coal seams
International Journal of Mining Science and Technology, 2017 To improve the effectiveness of control of surrounding rock and the stability of supports on longwall top-coal caving faces in steeply inclined coal seams, the stability of the roof structure and hydraulic supports was studied with physical simulation ...
Xiaomeng Li, Zhaohui Wang, Jinwang Zhang
doaj +1 more source
Remote Sensing, 2020 One of the main goals of modern silviculture is to emulate the structural complexity of old-growth forests. In this context, it is of advantage to identify a target state of structural complexity at the stand level and to analyze the spatial ...
Katharina Willim +5 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Kinematics of Polygonal Fault Systems: Observations from the Northern North Sea
Frontiers in Earth Science, 2017 Layer-bound, low-displacement normal faults, arranged into a broadly polygonal pattern, are common in many sedimentary basins. Despite having constrained their gross geometry, we have a relatively poor understanding of the processes controlling the ...
Thilo Wrona +4 more
doaj +1 more source
Comptes Rendus. Géoscience, 2004 High-frequency stratigraphic cycles (10 s to 100 s ka) often show, at a specific location, an alternation of ‘dynamic’ (proximal-energetic), and ‘non-dynamic’ (distal-pelagic) processes with time. When sedimentation is syn-deformation, these processes tend respectively to fill-up tectonically-induced topography or to drape it.
Castelltort, Sébastien +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source