Results 171 to 180 of about 402,737 (273)

Bioinformatic Analysis and Molecular Docking Identify Isorhamnetin Is a Candidate Compound in the Treatment of Pulmonary Artery Hypertension. [PDF]

Anatol J Cardiol
Shao C, Xia W, Liu Y.
europepmc   +1 more source

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Do bromine and surface-active substances influence the coastal atmospheric particle growth?

Heliyon
New particle formation (NPF) is considered a major source of aerosol particles and cloud condensation nuclei (CCN); however, our understanding of NPF and the subsequent particle growth mechanisms in coastal areas remains limited.
Kristijan Vidović, Samo Hočevar, Irena Grgić, Dino Metarapi, Iva Dominović, Boris Mifka, Asta Gregorič, Balint Alfoldy, Irena Ciglenečki   +8 more
doaj  

2'-Fucosyllactose as a prebiotic modulates the probiotic responses of Bifidobacterium bifidum. [PDF]

Curr Res Food Sci
Du J, Yang H.
europepmc   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Preserving the Biotransformation Potential of Activated Sludge in Time: Toward Reproducible Incubation Experiments for Persistence Assessment. [PDF]

Environ Sci Technol
Kalt M, Udressy CI, Yu Y, Colliquet A, Fenner K.   +4 more
europepmc   +1 more source

On the existence of a growth-inhibiting substance in the Chinese lemon /

, 1919
Howard S. Reed, Frederick Ferdinand Halma   +1 more
openalex   +2 more sources

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Methodological and Ethical Considerations in the Use of Chordate Embryos in Biomedical Research. [PDF]

Int J Mol Sci
Campitelli LMM, Lopes KP, de Lima IL, Ferreira FB, Isidoro ND, Ferreira GM, Ponce MCF, Ferreira MCO, Mendes LS, Marcelino PHR, Neves MM, Klein SG, Fonseca BB, Polveiro RC, da Silva MV.   +14 more
europepmc   +1 more source