Synergistic Effect of Substance P with Insulin and Insulin-Like Growth Factor-I on Epithelial Migration of the Transformed Human Corneal Epithelial Cells (SV-40) [PDF]
Phat Tran, Jonathan Kopel, Ted W. Reid
openalex +1 more source
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Nontargeted metabonomics analysis of Scorias spongiosa fruiting bodies at different growth stages
IntroductionScorias spongiosa is an edible fungus.MethodsIn this study, a nontargeted metabonomic analysis was conducted on the fruiting bodies of this fungus at five growth stages, and the differences in metabolites and the related metabolic pathways ...
Xiang Nong +14 more
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Chemometrics Analysis of the Components of Artemisia dracunculus L. Essential Oil with Growth Time
To explore the differences in the quality of Artemisia dracunculus L essential oil at different growth times, gas chromatography-mass spectrometry (GC-MS) was used to analyze the chemical components of Artemisia annua essential oil.
SUN Yi-ming +5 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Additional growth substances on spring wheat under conditions of moisture deficiency [PDF]
The research was carried out in the conditions of the Northern forest-steppe of the Tyumen region, with weather indicators in 2023, characterized by elevated temperatures and lack of moisture.
Timofeev Vyacheslav Nikolaevich
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This study was conducted to investigate the effects of composited functional bioactive substances on the growth performance and immune function of growth retardation (GR) pigs.
Xianze Wang +7 more
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Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source

