Results 61 to 70 of about 402,737 (273)
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Chemical reaction directed oriented attachment: from precursor particles to new substances [PDF]
arXiv, 2015 The oriented attachment (OA) of nanoparticles is an important mechanism for the synthesis of the crystals of inorganic functional materials, and the formation of natural minerals. For years it has been generally acknowledged that OA is a physical process, i.e., particle alignments and interface fusion via mass diffusion, not involving the formation of ...
arxiv
Mechanisms of Dendrites Occurrence during Crystallization: Features of the Ice Crystals Formation [PDF]
, 2007 Dendrites formation in the course of crystallization presents very general phenomenon, which is analyzed in details via the example of ice crystals growth in deionized water. Neutral molecules of water on the surface are combined into the double electric layer (DEL) of oriented dipoles; its field reorients approaching dipoles with observable radio ...
arxiv +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
FEBS Letters, EarlyView.In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti +3 more
wiley +1 more source
Nontargeted metabonomics analysis of Scorias spongiosa fruiting bodies at different growth stages
Frontiers in MicrobiologyIntroductionScorias spongiosa is an edible fungus.MethodsIn this study, a nontargeted metabonomic analysis was conducted on the fruiting bodies of this fungus at five growth stages, and the differences in metabolites and the related metabolic pathways ...
Xiang Nong +14 more
doaj +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Chemometrics Analysis of the Components of Artemisia dracunculus L. Essential Oil with Growth Time
Liang you shipin ke-jiTo explore the differences in the quality of Artemisia dracunculus L essential oil at different growth times, gas chromatography-mass spectrometry (GC-MS) was used to analyze the chemical components of Artemisia annua essential oil.
SUN Yi-ming +5 more
doaj +1 more source
Additional growth substances on spring wheat under conditions of moisture deficiency [PDF]
BIO Web of ConferencesThe research was carried out in the conditions of the Northern forest-steppe of the Tyumen region, with weather indicators in 2023, characterized by elevated temperatures and lack of moisture.
Timofeev Vyacheslav Nikolaevich
doaj +1 more source