Results 111 to 120 of about 6,351,909 (296)

Disentangling the Genetic Relationship Between Sleep and Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective A bidirectional relationship between sleep and epilepsy is well recognised, yet the biological mechanisms linking them remain poorly understood. Both have a genetic basis, with genome‐wide association studies (GWAS) capturing polygenic contributions.
Khang N. Le, Victoria E. Jackson, Rachel E. Stirling, Zachary F. Gerring, Remi Stevelink, Samuel F. Berkovic, Ingrid E. Scheffer, Philippa J. Karoly, Melanie Bahlo, Karen L. Oliver   +9 more
wiley   +1 more source

Macrophage–Fibroblast Crosstalk Governs Tumor Mechanics, as Revealed by Spatiotemporal Force Mapping in 3D Spheroids

Advanced Healthcare Materials, EarlyView.
This study shows crosstalk among tumor cells, fibroblasts, and macrophages alters the physical forces inside 3D tumor spheroids. Incorporating deformable microparticles in 3D tumor spheroids, the researchers mapped mechanical stresses spatially and with respect to tumor growth (temporally).
Kunal P. Pednekar, Daan Vorselen, Jai Prakash   +2 more
wiley   +1 more source

Estimates of Genetic and Phenotypic Trends of Growth Traits in Bali Cattle

Media Peternakan, 2012
The aim of this study was to estimate genetic and phenotypic trends for growth traits including birth (BW), weaning (WW) and yearling weight (YW) in Bali cattle.
A. Gunawan, R. Sari, Jakaria
doaj  

Studying Personality Traits Across Cultures: Philippine Examples [PDF]

, 2002
Trait perspectives are dominant in the study of personality cross-culturally. We review the questions addressed by researchers who study personality traits across cultures, including, among others, whether traits are used in all cultures to understand ...
Marcia S. Katigbak, Church, A. Timothy, A. Timothy Church, Katigbak, Marcia S.   +3 more
core   +1 more source

Modeling Early Metastatic Progression in Breast Cancer Using a Barrier‐Free, Perfusable Spheroid‐on‐a‐Chip Platform

Advanced Healthcare Materials, EarlyView.
Open‐port, barrier‐free microfluidic device for modeling early metastatic progression. A centrally positioned tumor spheroid releases invasive cells that migrate through the surrounding matrix and intravasate into endothelialized lateral channels.
Vira Sharko, Claudia Olaizola‐Rodrigo, Clara Bayona, Teodora Ranđelović, Rosa Monge, Estela Solanas, Sara Oliván, Ignacio Ochoa   +7 more
wiley   +1 more source

Estimates of Direct and Maternal Genetic Effects on Birth and Weaning Weights in Salem Black Goats from India

Ruminants
Growth traits in goats are impacted by both genetic and non-genetic variables; as such, it is critical to separate direct and maternal effects for reliable genetic assessment.
Muralidharan Jaganadhan, Thiruvenkadan Aranganoor Kannan, Jayanthi Duraisamy, Adel Salah Khattab, Oludayo Michael Akinsola, Sunday Olusola Peters   +5 more
doaj   +1 more source

Turning Observed Founder Alleles into Expected Relationships in an Intercross Population

G3: Genes, Genomes, Genetics, 2019
Pedigree-derived relationships for individuals from an intercross of several lines cannot easily account for the segregation variance that is mainly caused by loci with alternative alleles fixed in different lines.
Jilun Meng, Manfred Mayer, Erika Wytrwat, Martina Langhammer, Norbert Reinsch   +4 more
doaj   +1 more source

Bioprinted Stiffness‑Tunable Pancreatic Microniches to Decode Early Tumor Initiation Mechanisms

Advanced Healthcare Materials, EarlyView.
Stiffness‐tunable GelMA microniches generated by microvalve bioprinting preserve wild‐type acinar identity while revealing a nonlinear, Kras‐dependent response to matrix mechanics. Intermediate stiffness promotes acinar‐to‐ductal metaplasia and proliferation, defining a permissive mechanical window.
Aurelien Mazet, Charles Handschin, Theo Desigaux, Nathalie Dusserre, Marie‐Laure Stachowicz, Shane Fennell, Malou Lea, Silvia Arcucci, Benoît Thibault, Jean‐Christophe Fricain, Julie Guillermet‐Guibert, Hugo Oliveira   +11 more
wiley   +1 more source

Double-negative feedback loop between IGF2BP2 and miR-196-5p inhibits the proliferation and differentiation of primary chicken myoblasts

Poultry Science
Skeletal muscle, the primary edible component of chicken, plays a crucial role in determining meat yield and quality. It was reported that IGF2BP2 plays a critical role in the growth and development of mammals muscle, but its role in poultry muscle ...
Wenjin Shen, Li Zhang, Shudai Lin, Yuling Wu, Lei Li, Zihao Zhang   +5 more
doaj   +1 more source

Can Elastomers Combine Stiffness, Toughness and Fatigue Resistance?

Advanced Materials, EarlyView.
This review studies how the molecular and macroscopic architecture of elastomers influence their mechanical properties including: stiffness, stretchability, toughness, fatigue resistance, and damping behavior. By linking the structure to performance, it proposes design principles for advanced elastomeric systems that combine mechanical properties ...
Eva Baur, Esther Amstad
wiley   +1 more source