Targeting RANKL Prevents Bone Loss, Improves Muscle Function and Extends Lifespan in Progeroid Mice
Aging Cell, Volume 25, Issue 8, August 2026.Targeting of RANKL by genetic and pharmacological approaches ameliorates key features of the progeroid phenotype in Zmpste24−/− mice. RANKL intervention restores bone mass, improves muscle phenotype, and extends survival. These findings support further exploration of RANKL‐targeted therapies for Hutchinson‐Gilford progeria syndrome.
Sandra Freitas‐Rodríguez +11 more
wiley +1 more source
Geospatial assessment of habitat degradation and climate impacts on migratory crane habitat in Pakistan's Wetland ecosystems. [PDF]
Sci RepSuliman M +9 more
europepmc +1 more source
Speech and Language Markers of Bipolar Disorder: Challenges and Opportunities
Bipolar Disorders, Volume 28, Issue 5, August 2026.ABSTRACT Background Clinicians aspire to predict the emergence of Bipolar Disorder (BD) in a timely manner. To accomplish this, markers reflecting mental states that can be gathered non‐invasively and at large scale are needed. Here, we systematically evaluate evidence relating speech‐based markers to mood states in BD.
Farida Zaher +4 more
wiley +1 more source
Prognostic impact of p53 and HER2 immunohistochemistry profiles in colorectal carcinoma. [PDF]
Pathol Oncol ResGrus M +6 more
europepmc +1 more source
Breeding 5.0: Artificial intelligence (AI)‐decoded germplasm for accelerated crop innovation
Journal of Integrative Plant Biology, Volume 68, Issue 8, Page 2340-2352, August 2026.This review synthesizes applications of AI and robotics for germplasm characterization and breeding, proposing the Breeding 5.0 framework with its “Breeding Flywheel”. By decoding germplasm's multidimensional architecture, AI drives data‐empowered automation cycles to accelerate germplasm innovation, redefining solutions for global food security ...
Jiayi Fu +4 more
wiley +1 more source
QRNN-GRU framework for automatic argument and annotation extraction in medical drug reviews. [PDF]
Sci RepAltameem E, Alnuem M, Albassam S.
europepmc +1 more source
Status and trends of the Common Crane Grus grus on the western route
Bird conservation international, 1998 J. Guzmán +3 more
semanticscholar +1 more source
High Relative Accuracy Computations With Covariance Matrices of Order Statistics
Mathematical Methods in the Applied Sciences, Volume 49, Issue 11, Page 11794-11810, 30 July 2026.ABSTRACT In many statistical applications, numerical computations with covariance matrices need to be performed. The error made when performing such numerical computations increases with the condition number of the covariance matrix, which is related to the number of variables and the strength of the correlation between the variables. In a recent work,
Juan Baz +3 more
wiley +1 more source
Comparative Analysis of Gut Microbiota Among Captive Waterbird Species: Effects of Diet and Environmental Factors. [PDF]
Vet Med SciLiu H, Bo T, Li J, Zhang Y, Zhou H.
europepmc +1 more source
Vision Transformers for Modeling of Nonlinear Heterogeneous Materials
International Journal for Numerical Methods in Engineering, Volume 127, Issue 14, 30 July 2026.ABSTRACT Multiscale simulations of nonlinear heterogeneous materials and composites are challenging due to the prohibitive computational costs of high‐fidelity simulations. Recently, machine learning (ML) based approaches have emerged as promising alternatives to traditional multiscale methods.
Yijing Zhou, Shabnam J. Semnani
wiley +1 more source