Results 31 to 40 of about 153,276 (258)

ESTUDO DE DOADORES COM TESTE DE ÁCIDO NUCLEICO ALTERADO PARA HEPATITE B, C E HIV E CORRELAÇÃO COM SOROLOGIA

Hematology, Transfusion and Cell Therapy, 2023
Introdução: Uma das maiores preocupações relacionadas à segurança transfusional é a possibilidade de transmissão de doenças através do sangue transfundido, entre as quais se encontram as hepatites B, C e o HIV.
APC Rodrigues, RA Bento, DE Rossetto, JAD Santos, ACA Pitol, AP Sessin, FJ Benatti, SMC Lira, NJ Moitinho, CLA Rocha, EC Ferreira   +10 more
doaj   +1 more source

Effect of Thiabendazole(TBZ)on Glutathione(GSH) and GSH Related Enzymes in Mice Liver

YAKUGAKU ZASSHI, 2000
The present study examines the effects of thiabendazole (TBZ), its metabolites, 5-hydroxythiabendazole (5-OH TBZ) and 2-acetylbenzimidazole (ABI), and structural related compounds, thiazoles and thioamides on glutathione (GSH) concentration and GSH-related enzymes in the livers of ICR 11 week-old female mice.
C, Toda, T, Yasui, K, Hashizume, H, Nagano   +3 more
openaire   +3 more sources

PROTOCOLO DE HEMORRAGIA OBSTÉTRICA NO PROGRAMA DE BONS PRINCÍPIOS DE PRÁTICAS MÉDICAS (PBM)

Hematology, Transfusion and Cell Therapy
Introdução e objetivo: A hemorragia obstétrica é uma das principais causas de mortalidade materna, exigindo uma abordagem eficaz e padronizada para sua prevenção e tratamento.
RCB Soares, AA Magagna, KJD Olio, NV Almeida, KCG Alves, AHV Almeida, JED Giacomo, JAD Santos, LPS Fontenele, FCV Perini, EB Souza, RA Bento, DE Rossetto   +12 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

ANÁLISE DO CONTROLE DE QUALIDADE DOS CONCENTRADOS DE PLAQUETAS RANDÔMICAS PRODUZIDOS PELO BANCO DE SANGUE DE SÃO PAULO (GRUPO GSH)

Hematology, Transfusion and Cell Therapy
Objetivo: Avaliar a qualidade da produção de concentrado de plaquetas (CP5) no Banco de Sangue de São Paulo (Grupo GSH) no período de janeiro de 2022 a dezembro de 2023. Material e métodos: Foram avaliados dados dos relatórios do sistema informatizado do
AP Sessin, RA Bento, JAD Santos, DE Rossetto, APC Rodrigues, ACA Pitol   +5 more
doaj   +1 more source

Contribution of mitochondrial GSH transport to matrix GSH status and colonic epithelial cell apoptosis [PDF]

Free Radical Biology and Medicine, 2008
Previously, we showed that cellular glutathione/glutathione disulfide (GSH/GSSG) play an important role in apoptotic signaling, and early studies linked mitochondrial GSH (mtGSH) loss to enhanced cytotoxicity. The current study focuses on the contribution of mitochondrial GSH transport and mitochondrial GSH/GSSG status to apoptosis initiation in a ...
Magdalena L, Circu, Cynthia, Rodriguez, Ronald, Maloney, Mary Pat, Moyer, Tak Yee, Aw   +4 more
openaire   +2 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

ANÁLISE COMPARATIVA DOS RESULTADOS DO CONTROLE DE QUALIDADE DOS CONCENTRADOS DE HEMÁCIAS FILTRADOS PRODUZIDOS NO BANCO DE SANGUE DE SÃO PAULO (GRUPO GSH)

Hematology, Transfusion and Cell Therapy
Objetivo: Comparar os parâmetros das análises do controle de qualidade realizados dos concentrados de hemácias filtrados (CHF), produzidos no Banco de Sangue de São Paulo, no período de 2022 e 2023.
AP Sessin, RA Bento, JAD Santos, DE Rossetto, APC Rodrigues, ACA Pitol   +5 more
doaj   +1 more source

The Glutathione Derivative, GSH Monoethyl Ester, May Effectively Whiten Skin but GSH Does Not [PDF]

International Journal of Molecular Sciences, 2016
Glutathione in its reduced form (GSH) is an antioxidant and also is involved in pheomelanin formation. Thus, it has been long believed that GSH has a skin whitening effect. However, its actual or direct effect is unproven. We evaluated the anti-melanogenic effects of GSH and its derivatives in vitro.
Bo Chung, So Choi, Ik Moon, Chun Park, Young-Hoon Kim, Sung Chang   +5 more
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source