Results 51 to 60 of about 153,861 (265)
PREVALÊNCIA DE SOROLOGIA POSITIVA PARA SÍFILIS DOS DOADORES DO BANCO DE SANGUE SÃO PAULO NO ANO 2022
Hematology, Transfusion and Cell Therapy, 2023 Objetivo: A sífilis é uma doença infecciosa, que tem como agente etiológico o Treponema pallidum e é problema de saúde pública global, que gera preocupação, pois além de ser uma doença sexualmente transmissível, também pode ser transmitida por transfusão
JAD Santos +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Hematology, Transfusion and Cell Therapy, 2023 Introdução: A cirurgia cardíaca é uma das principais cirurgias de grande porte com alto potencial para perda sanguínea perioperatória e subsequente transfusão de sangue e hemoderivados, com isso todo procedimento requer reserva de hemocomponentes.
MCL Silva +5 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.A GSH‐responsive AIE nanoplatform (TSH NPs) with RGD‐mediated tumor targeting co‐delivers a photosensitizer (TPA) and HCPT for extrahepatic cholangiocarcinoma. The system synergistically enhances PDT and chemotherapy by suppressing HIF‐1α/VEGF‐driven hypoxic adaptation, effectively overcoming PDT resistance.
Yong Qu +19 more
wiley +1 more source
Hematology, Transfusion and Cell Therapy, 2023 Objetivo: Verificar os motivos da inaptidão clínica em relação ao sexo doador do Banco de Sangue São Paulo no período de janeiro a dezembro de 2022. Materiais e método: O presente estudo tem caráter descritivo com abordagem quantitativa utilizando os ...
RA Bento +5 more
doaj +1 more source
Advanced Materials, EarlyView.Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song +14 more
wiley +1 more source
Hematology, Transfusion and Cell TherapyResumo: Relato de caso de paciente de 44 anos com Doença Falciforme (DF) sem tratamento otimizado, com úlceras crônicas de membros inferiores desde 2017 e que, após o início do programa de transfusões de troca obteve melhora expressiva e resolução quase ...
PG Moura +8 more
doaj +1 more source
Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects
Advanced Materials, EarlyView.Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley +1 more source
The kinetics of oxidation of GSH by protein radicals [PDF]
Biochemical Journal, 2005 Current studies provide evidence that proteins are initial targets of ROS (reactive oxygen species) in biological systems and that the damaged proteins can in turn damage other cell constituents. This study was designed to test the possibility that protein radicals generated by ROS can oxidize GSH and assess the probability of this reaction in vivo by ...
Nauser, Thomas +2 more
openaire +4 more sources
Advanced Materials, EarlyView.Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou +5 more
wiley +1 more source