Results 71 to 80 of about 273,251 (302)

Biomimetic Copper‐Doped Nano‐Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia

open access: yesAdvanced Healthcare Materials, EarlyView.
We developed a novel copper‐doped aluminum nano‐adjuvant (CuNA) to overcome cytarabine resistance in acute myeloid leukemia (AML). CuNA effectively sensitizes drug‐resistant AML cells to cytarabine by inducing mitochondrial dysfunction and inhibiting HMGCR/GPX4 to amplify ferroptosis.
Chao He   +10 more
wiley   +1 more source

PERFIL DO ABASTECIMENTO DE HEMOCOMPONENTES NA REGIONAL SÃO PAULO INTERIOR E PARANÁ, PELO BANCO DE SANGUE RIBEIRÃO PRETO – GRUPO GSH

open access: yesHematology, Transfusion and Cell Therapy
Introdução: O gerenciamento de estoque de hemocomponentes é imprescindível para alcançar equilíbrio entre oferta e demanda. Para o atendimento das demandas, o Banco de Sangue Ribeirão Preto realiza em média 870 coleta de bolsas/mês entre sangue total e ...
LCM Silva   +9 more
doaj   +1 more source

Organelle Localization‐Induced Bio‐Orthogonal Polymerization (OLIBOP) for Photostable Super‐Resolution Live‐Cell Imaging

open access: yesAdvanced Healthcare Materials, EarlyView.
Organelle localization‐induced biorthogonal polymerization enables direct synthesis of photostable poly‐AIEgens within targeted organelles for super‐resolution live‐cell imaging. ABSTRACT Real‐time monitoring of dynamic biological processes demands fluorescent probes that can withstand prolonged light exposure without photobleaching—a critical ...
Gaeun Park   +4 more
wiley   +1 more source

ANÁLISE DO CONTROLE DE QUALIDADE DE SANGUE TOTAL E HEMOCOMPONENTES PRODUZIDOS, NO BANCO DE SANGUE DE SÃO PAULO

open access: yesHematology, Transfusion and Cell Therapy, 2023
Objetivo: O trabalho visa apresentar os resultados das análises do controle de qualidade dos hemocomponentes produzidos no banco de sangue. Material e métodos: Os resultados do controle de qualidade foram obtidos através de relatórios do sistema ...
APC Sessin   +5 more
doaj   +1 more source

Copper–Collagen Interactions Regulate the Mechanical and Invasive Properties of Tumor Spheroids

open access: yesAdvanced Healthcare Materials, EarlyView.
Ionic copper is investigated as a modulator of tumor spheroid growth and invasiveness in a 3D microfluidic glioblastoma model. Copper exposure alters metabolic activity, cytoskeletal organization, protrusion dynamics, and EMT‐related phenotypes in a dose‐ and timing‐dependent manner, revealing how copper bioavailability shapes tumor aggressiveness ...
Paula Guerrero‐López   +5 more
wiley   +1 more source

PERFIL DE DOADORES COM SOROLOGIA POSITIVA PARA CHAGAS DOS DOADORES DE SANGUE DO GRUPO GSH NO ANO 2022

open access: yesHematology, Transfusion and Cell Therapy, 2023
Objetivos: A Doença de Chagas (DC), é causada pelo protozoário Trypanosoma cruzi (T.cruzi) , que é transmitido pela picada ou deposição de fezes de vetores contaminados (barbeiros), sobre os tecidos cutâneos e mucosas do indivíduo.
JAD Santos   +5 more
doaj   +1 more source

Nanobody‐Conjugated Theranostic Prodrug Targeting αvβ3 Integrin Enables Precision Cancer Therapy With Real‐Time Imaging

open access: yesAdvanced Healthcare Materials, EarlyView.
The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.
Sanu Karan   +13 more
wiley   +1 more source

GSH23.0-0.7+117, a neutral hydrogen shell in the inner Galaxy

open access: yes, 2004
GSH23.0-0.7+117 is a well-defined neutral hydrogen shell discovered in the VLA Galactic Plane Survey (VGPS). Only the blueshifted side of the shell was detected. The expansion velocity and systemic velocity were determined through the systematic behavior
A. R. Taylor   +14 more
core   +2 more sources

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

open access: yesAdvanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang   +4 more
wiley   +1 more source

IMPACTO DA TRANSFUSÃO DE TROCA AUTOMATIZADA EM PACIENTE COM DOENÇA FALCIFORME DE EVOLUÇÃO GRAVE CURSANDO COM HEMATOPOIESE EXTRAMEDULAR– RELATO DE CASO

open access: yesHematology, Transfusion and Cell Therapy
Resumo: Relato de caso de paciente de 15 anos com Doença Falciforme (DF)de evolução grave, com surgimento de lesão paravertebral evidenciada em exame de ressonância nuclear magnética (RNM), sugerindo hematopoiese extramedular (HEM) e que obteve resolução
PG Moura   +9 more
doaj   +1 more source

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