Results 41 to 50 of about 12,653 (214)

Supplemental Ascorbate Diminishes DNA Damage Yet Depletes Glutathione and Increases Acute Liver Failure in a Mouse Model of Hepatic Antioxidant System Disruption

Antioxidants, 2021
Cellular oxidants are primarily managed by the thioredoxin reductase-1 (TrxR1)- and glutathione reductase (Gsr)-driven antioxidant systems. In mice having hepatocyte-specific co-disruption of TrxR1 and Gsr (TrxR1/Gsr-null livers), methionine catabolism ...
Colin G. Miller, Jean A. Kundert, Justin R. Prigge, Julie A. Amato, Allison E. Perez, Lucia Coppo, Gabrielle N. Rizzo, Michael P. Kavanaugh, David J. Orlicky, Colin T. Shearn, Edward E. Schmidt   +10 more
doaj   +1 more source

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

Advanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan, Qiu Dai, Yanhui Wang, Jiaxuan Gu, Chengyun Wang, Weicheng Xu, Xinru Gao, Jiageng Cheng, Wentao Geng, Xiaowen Wu, Haihang Li, Xiaoyun He, Shengwei Fu, Longjiao Zhu, Wentao Xu   +14 more
wiley   +1 more source

Tools in Marketing Research: Exploring Emotional Responses to Stimuli

Scientific Annals of Economics and Business
Electromyography (EMG), galvanic skin responses (GSR), and electrocardiogram (ECG) tools have been used to investigate emotional responses to marketing stimuli, encompassing advertisements, product packaging, and brand logos.
Ahmed Alsharif, Ahmad Khraiwish
doaj   +1 more source

Eyes Closing and Drowsiness in Human Subjects Decrease Baseline Galvanic Skin Response and Active Palmar Sweating: Relationship Between Galvanic Skin and Palmar Perspiration Responses

Frontiers in Physiology, 2020
We previously constructed a perspiration ratemeter for the measurement of palmar sweating in human subjects. Although galvanic skin response (GSR) has been used to evaluate emotional responses in human subjects, little is known about the relationships ...
Hideya Momose, Norimasa Morimitsu, Eiji Ikeda, Shigeki Kanai, Masao Sakaguchi, Toshio Ohhashi   +5 more
doaj   +1 more source

MPP8 Facilitates DNA DSB Repair via NHEJ to Promote Chemoresistance of TNBC Independent of Methyl‐H3K9 Binding

Advanced Science, EarlyView.
Chemoresistance is often linked to elevated DNA repair. MPP8 is found to promote breast cancer chemoresistance as a novel NHEJ accessory factor independent of its epigenetic functions. Through multiple protein interactions, MPP8 facilitates association of DNAPK and ligase complexes to promote DNA repair progression.
Rupa Kumari, Jia Fang
wiley   +1 more source

Gender Variations in the Effects of Number of Organizational Memberships, Number of Social Networking Sites, and Grade-Point Average on Global Social Responsibility in Filipino University Students

Europe's Journal of Psychology, 2016
The study seeks to estimate gender variations in the direct effects of (a) number of organizational memberships, (b) number of social networking sites (SNS), and (c) grade-point average (GPA) on global social responsibility (GSR); and in the indirect ...
Romeo B. Lee, Rito V. Baring, Madelene A. Sta. Maria   +2 more
doaj   +1 more source

Behaviorally Adaptive and Inclusive Advanced Driver‐Assistance Systems

Advanced Intelligent Systems, EarlyView.
Advanced driver‐assistance systems (ADASs) are mapped as evolving human‐centered, adaptive technologies linking sensing, driver monitoring, AR/HUD interfaces, patents, regulation, and inclusive design. The review identifies gaps in real‐world evidence, diverse‐driver validation, gaze metrics, and governance, outlining a roadmap for safer, behaviorally ...
Jana Skirnewskaja, Mardavij Roozbehani, Munther A. Dahleh   +2 more
wiley   +1 more source

Airborne and Dermal Collection Methods of Gunshot Residue for Toxicity Studies

Applied Sciences, 2022
Gunshot residue (GSR) has potential negative health effects on humans as a result of inhalation and dermal exposure to the chemical and physical characteristics of GSR such as Pb, Sb, Ba, nitrocellulose, nitroglycerine, and particulate size fraction ...
Samuel Cole Smith, Oscar Beau Black, Courtney Roper   +2 more
doaj   +1 more source

Comprehensive Characterization of Acer truncatum Leaf Extract: Identification of Systemic Metabolites and Effects on Performance, Antioxidant Status, and Intestinal Microbiota in Laying Hens

Animal Research and One Health, EarlyView.
Dietary A. truncatum leaf extract is absorbed and improves laying performance in aged hens by enhancing systemic antioxidant capacity and modulating the gut microbiota. ABSTRACT The demand for natural feed additives is considerably increasing in the antibiotic‐free feed era.
Kailong Qin, Jiantao Yang, Minglu Gao, Xiaozhao Tao, Xin Yang, Yanli Liu, Xiaojun Yang   +6 more
wiley   +1 more source

The glutathione reductase GSR-1 determines stress tolerance and longevity in Caenorhabditis elegans. [PDF]

PLoS ONE, 2013
Glutathione (GSH) and GSH-dependent enzymes play a key role in cellular detoxification processes that enable organism to cope with various internal and environmental stressors.
Kai Lüersen, Dirk Stegehake, Jens Daniel, Mike Drescher, Irene Ajonina, Caroline Ajonina, Patrick Hertel, Christian Woltersdorf, Eva Liebau   +8 more
doaj   +1 more source