Results 71 to 80 of about 548,206 (222)

Sensitivity analysis of the GTN damage parameters at different temperature for dynamic fracture propagation in X70 pipeline steel using neural network

Fracture and Structural Integrity, 2021
In this paper, the initial and maximum load was studied using the Finite Element Modeling (FEM) analysis during impact testing (CVN) of pipeline X70 steel.
Abdelmoumin Ouladbrahim, Idir Belaidi�, Samir Khatir, Magd Abdel Wahab, Erica Magagnini, Roberto Capozucca   +5 more
doaj   +1 more source

Sestrins are evolutionarily conserved mediators of exercise benefits. [PDF]

, 2020
Exercise is among the most effective interventions for age-associated mobility decline and metabolic dysregulation. Although long-term endurance exercise promotes insulin sensitivity and expands respiratory capacity, genetic components and pathways ...
Brooks, Susan V, Cho, Chun-Seok, Cobb, Tyler, Davis, Carol, Gu, Bondong, Karin, Michael, Kim, Boyoung, Kim, Myungjin, Kowalsky, Allison H, Lee, Jun Hee, Namkoong, Sim, Ro, Seung-Hyun, Semple, Ian, Sujkowski, Alyson, Wessells, Robert J   +14 more
core   +2 more sources

Age‐Associated Dysregulation of Postsynaptic Mitochondria Perturbs Reinnervation Kinetics

Aging Cell, Volume 25, Issue 1, January 2026.
We show that aging results in postsynaptic mitochondrial loss at the neuromuscular junction and impaired muscle reinnervation. In vivo CRISPR knockout of mitochondrial genes, CHCHD10 and CHCHD2, in young muscles led to fragmented endplates, aberrant innervation, and impaired transcriptional maturation of sub‐synaptic myonuclei during regeneration ...
Steve D. Guzman, Paula M. Fraczek, Klimentini Itsani, Esraa K. Furati, Devin Juros, Grace Kenney, Gregorio Valdez, Joe V. Chakkalakal, Carlos A. Aguilar   +8 more
wiley   +1 more source

Investigation on hydrogen embrittlement and failure characteristics of Zr-4 cladding based on the GTN method

Nuclear Materials and Energy, 2023
Based on the classical Gursone-Tvergaarde-Needleman (GTN) method, a theoretical model was developed and applied to predict the mechanical behavior and fracture characteristics of hydrogenated zirconium cladding.
Yangbin Deng, Haoyu Liao, Yanan He, Yuan Yin, Marco Pellegrini, Guanghui Su, Koji Okamoto, Yingwei Wu   +7 more
doaj   +1 more source

Adipocytokine levels mark endothelial function in normotensive individuals [PDF]

, 2012
BACKGROUND: Endothelial dysfunction is an independent risk factor for cardiovascular events. Inflammatory mediators released by the adipose tissue can lead to local insulin resistance and endothelial dysfunction.
Anna Solini, Eleonora Santini, Emiliano Duranti, Francesco Stea, Lorenzo Ghiadoni, Rosa Bruno, Stefano Taddei   +6 more
core   +1 more source

Pyrolysis of Onion Peel Waste: Investigation of Comprehensive Pyrolysis Index, Reaction Mechanism, Kinetic, and Thermodynamic Properties Using TGA Analysis

International Journal of Energy Research, Volume 2026, Issue 1, 2026.
The rising demand for onion production results in significant waste, harming the environment. Onion waste is unsuitable for animal feed and difficult to dispose of due to its strong odor and potential for phytopathogen growth. Pyrolysis is a promising method for repurposing food waste, requiring minimal infrastructure and offering rapid processing and ...
Tesfa Nega Gesese, Alebel Abebaw Teshager, Prakash Bhuyar   +2 more
wiley   +1 more source

Numerical simulation and experimental investigation of ductile fracture in SPIF using modified GTN model

MATEC Web of Conferences, 2015
Incremental sheet forming (ISF) is a relatively new flexible forming process with excellent adaptability to CNC milling machines due to the fact that it does not require any high capacity presses or dies of a specific shape and this makes the process ...
Gatea Shakir, Lu Bin, Ou Hengan, McCartney Graham   +3 more
doaj   +1 more source

Damage evolution of 7075 aluminum alloy basing the Gurson Tvergaard Needleman model under high temperature conditions

Journal of Materials Research and Technology, 2022
Based on the Gurson-Tvergaard-Needleman (GTN) damage model, the damage evolution and ductile fracture of 7075 aluminum alloy sheets during the tensile process were predicted. First, the true stress–strain curve and micro morphology of 7075 aluminum alloy
Hongchao Ji, Zheng Ma, Xiaomin Huang, Wenchao Xiao, Baoyu Wang   +4 more
doaj   +1 more source

ROS‐Scavenging Multifunctional Microneedle Patch Facilitating Wound Healing

Advanced Healthcare Materials, Volume 14, Issue 31, December 8, 2025.
A reactive oxygen species (ROS) scavenging and immunomodulatory microneedle patch based on hyaluronic acid methacrylate (HaMA) and Flightless I (Flii)‐siRNA‐laden arginine functionalized poly (β‐amino ester)/alginate particles is developed for chronic wound healing applications.
Mahshid Kharaziha, Sahar Salehi, Mahshid Shokri, Seyed Mohsen Ahmadi Tafti, Thomas Scheibel   +4 more
wiley   +1 more source

Mitochondrial oxidative stress and nitrate tolerance – comparison of nitroglycerin and pentaerithrityl tetranitrate in Mn-SODmice [PDF]

, 2006
Background Chronic therapy with nitroglycerin (GTN) results in a rapid development of nitrate tolerance which is associated with an increased production of reactive oxygen species (ROS).
Hanke Mollnau, Philip Wenzel, Matthias Oelze, Nicolai Treiber, Andrea Pautz, Eberhard Schulz, Swenja Schuhmacher, Kurt Reifenberg, Dirk Stalleicken, Karin Scharffetter-Kochanek, Hartmut Kleinert, Thomas Münzel, Andreas Daiber, J Abrams, T Munzel, T Munzel, E Schulz, G Abou-Mohamed, G Abou-Mohamed, T Munzel, A Warnholtz, E Bassenge, B Fink, T Munzel, U Jurt, T Gori, R Keimer, M Skatchkov, A Daiber, M Schwemmer, U Hink, Z Chen, Z Chen, K Sydow, A Daiber, A Daiber, IS Mackenzie, Y Li, S Oberle, S Oberle, M Strassburger, A Daiber, T Munzel, S Raha, A Daiber, CJ Edgell, H Li, KJ Livak, T Munzel, DJ Senior, CS Tsai, P Needleman, P Needleman, C Di Mauro, N Grosser, S Immenschuh, T Yamaguchi, M Minetti, R Stocker, LE Otterbein, T Morita, B Brune, DP Converso, N Grosser, A Prawan   +64 more
core   +1 more source