Results 71 to 80 of about 13,842,156 (196)

Remote Residue Substitution and Macrocyclization Preorganize a β‐Hairpin Peptide and Enhance β‐Catenin Binding

open access: yesChemistryEurope, Volume 4, Issue 9, September 2026.
A single amino acid substitution combined with peptide macrocyclization enhances the affinity of a β‐hairpin peptide for the oncogenic protein β‐catenin. Crystallographic and molecular dynamics analyses reveal that solution‐state preorganization through β‐hairpin stabilization, rather than direct protein contacts, is responsible for the increased ...
Michael H. N. Meulendijks   +11 more
wiley   +1 more source

FIGO staging for gestational trophoblastic neoplasia: 2026

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 174, Issue 3, Page 1172-1180, September 2026.
Abstract Gestational trophoblastic neoplasia (GTN) encompasses a wide range of diseases, which include choriocarcinoma, placental site trophoblastic tumor, epithelioid trophoblastic tumor, and post‐molar persistent or rising levels of human chorionic gonadotrophin.
Hextan Y. S. Ngan   +10 more
wiley   +1 more source

Failure and strain gradient analyses in incremental forming using GTN model

open access: yesInternational Journal of Lightweight Materials and Manufacture, 2019
Single point incremental forming (SPIF) process is gaining popularity for rapid manufacturing of complex 3D shapes. The present study is aimed at numerically predicting the failure using the Gurson-Tvergaard-Needleman (GTN) model and further clarifying ...
Muhammad Ilyas   +2 more
doaj   +1 more source

Impact of Heated Versus Unheated Cooking Oil on Postprandial Vascular Function and Metabolism

open access: yesLipids, Volume 61, Issue 5, Page 555-562, September 2026.
ABSTRACT The impact of repeated heating of seed‐based culinary oils on cardiometabolic health has not been well established. Heating oils to high temperatures (> 150°C) causes lipid peroxidation, thus generating potentially harmful compounds that may impair vascular function. This randomized, single‐blind, crossover study investigated the acute effects
Rosiered Brownson‐Smith   +5 more
wiley   +1 more source

Parametric study of the ductile damage by the Gurson–Tvergaard–Needleman model of structures in carbon steel A48-AP

open access: yesJournal of Materials Research and Technology, 2015
This part of study is devoted to the numerical simulation of axisymmetric notched specimens in order to study the phenomenon of nucleation by Gurson–Tvergaard–Needleman model (GTN).
Abdelkader Slimane   +3 more
doaj   +1 more source

School achievement in the Brazilian rural Amazon: An analysis of the interaction among motor, cognitive and environmental factors

open access: yesBritish Journal of Developmental Psychology, Volume 44, Issue 3, Page 590-602, September 2026.
Abstract A cross‐sectional study of 106 students (7–12 years) from a rural school in the Brazilian Amazon investigated the interaction among motor, cognitive and environmental factors on school achievement using network analysis. Students with good school performance were significantly older and showed superior global physical fitness, motor ...
Douglas Vieira   +3 more
wiley   +1 more source

Guidance for Specialised Cancer Nursing of People With Gynaecological Cancers: A Scoping Review

open access: yesJournal of Clinical Nursing, Volume 35, Issue 9, Page 3636-3649, September 2026.
ABSTRACT Background Gynaecological cancer nurses are crucial to the delivery of quality, specialised care to meet the needs of people with these cancers. The extent of evidence‐based guidance to support nursing care is unknown. Aim To identify and describe existing international guidance for specialised gynaecological cancer nursing care.
Natalie Williams   +4 more
wiley   +1 more source

Evaluation of residual stress and its influence on fracture performance of Q690 thick plate butt welded joint

open access: yesZhongguo Jianchuan Yanjiu
ObjectiveThis study aims to investigate the complex welding residual stress of high-strength steel thick plate with multi-pass welding, and examines the influence of such stress on the fracture behavior of welded joints.
Jiangchao WANG   +6 more
doaj   +1 more source

Simulation of ductile fracture using GTN micromechanical damage model [PDF]

open access: yes, 2021
V magistrski nalogi je obravanavano mikromehansko modeliranje duktilnega loma z uporabo Gurson-Tvergaard-Needleman mikromehanskega poškodbenega materialnega modela (GTN), z namenom ugotavljanja primernosti tega modela za numerično določanje ...
Jerenec, Filip
core  

Modelling of crack propagation in miniaturized and normal SENB specimens based on local failure criterion

open access: yesFracture and Structural Integrity
The use of miniaturized specimen testing methods is a promising way to solve the problem of limited materials in RPV monitoring programs. The use of miniature specimens allows the evaluation of fracture toughness from other specimen materials used.
Bernadett Spis�k   +3 more
doaj   +1 more source

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