Glyceryl Trinitrate: History, Mystery, and Alcohol Intolerance [PDF]
Molecules, 2021 Glyceryl trinitrate (GTN) is one of the earliest known treatments for angina with a fascinating history that bridges three centuries. However, despite its central role in the nitric oxide (NO) story as a NO-donating compound, establishing the precise ...
Russell Pearson, Anthony Butler
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Can Topical Glyceryl Trinitrate be Effective in the Treatment of Levator Ani Syndrome? [PDF]
The Turkish Journal of GastroenterologyBackground/Aims: Levator ani syndrome (LAS) is a pathology that is both difficult to diagnose and treat. The effectiveness of current treatments, which are mostly administered with special devices in advanced healthcare centers, is controversial. The aim
Fırat Canlıkarakaya, Serhat Ocaklı
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Myocardial Energy Response to Glyceryl Trinitrate: Physiology Revisited [PDF]
Frontiers in Physiology, 2021 Objective: Although intravenous nitrates are commonly used in clinical medicine, they have been shown to increase myocardial oxygen consumption and inhibit complex IV of the electron transport chain.
William D. Watson +7 more
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Paramacular Acute Middle Maculopathy Associated with Glyceryl Trinitrate [PDF]
Case Reports in Ophthalmological Medicine, 2021 An unusual case of nitroglycerin-induced Paracentral Acute Middle Maculopathy (PAMM) is presented. A 50-year-old patient with sudden vision loss and scotoma was followed up with swept-source optical coherence tomography (SS-OCT), optical coherence ...
Tryfon Rotsos +5 more
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Effect of glyceryl trinitrate and clevidipine administration on CT angiogram findings in dogs undergoing prostatic artery embolization for prostatic carcinoma. [PDF]
PLoS ONEObjectivesThe primary aim of this study was to evaluate the effects of vasodilator administration on CT angiography (CTA) prostatic artery diameter and peak opacification in dogs with prostatic carcinoma prior to prostatic artery embolization (PAE ...
Maureen A Griffin +7 more
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Glyceryl Trinitrate Enhances Caffeine Cytotoxicity Under Metabolic Stress in Cancer Cells [PDF]
MoleculesCancer cell metabolism represents a critical therapeutic target, particularly under conditions of metabolic stress induced by glycolysis inhibition.
Vesna Zeljković +6 more
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Rapid Intravenous Glyceryl Trinitrate in Ischemic Damage (RIGID) After Stroke: Rationale, Design and Protocol for a Prospective Randomized Controlled Trial [PDF]
Frontiers in Neurology, 2021 Background: Despite intravenous thrombolysis and endovascular therapy for acute ischemic stroke (AIS), many survivors still have varying degrees of disability.
Lipeng Cai +12 more
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Health Technology Assessment, 2019 Background: Retained placenta is associated with postpartum haemorrhage and can lead to significant maternal morbidity if untreated. The only effective treatment is the surgical procedure of manual removal of placenta, which is costly, requires skilled ...
Fiona C Denison +13 more
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Comparative Study of 0.2% Glyceryl Trinitrate Ointment for Pain Reduction after Hemorrhoidectomy Surgery [PDF]
The Surgery Journal, 2019 Context Hemorrhoid is one of the most common diseases in both, men and women, affecting half of the world's population over the age of 50. Aims The aim of this study was to evaluate the analgesic effects of local ointment of glyceryl ...
Sepideh Vahabi +3 more
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Prehospital transdermal glyceryl trinitrate for ultra-acute ischaemic stroke: data from the RIGHT-2 randomised sham-controlled ambulance trial [PDF]
Stroke and Vascular NeurologyBackground The effect of transdermal glyceryl trinitrate (GTN, a nitrovasodilator) on clinical outcome when administered before hospital admission in suspected stroke patients is unclear. Here, we assess the safety and efficacy of GTN in the prespecified
Keith W Muir +21 more
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