Results 21 to 30 of about 16,833 (197)

A Comparative Study of Topical Diltiazem (2%) with Topical Glyceryl Trinitrate (0.2%) as a Conservative Treatment for Anal Fissure [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2020
Introduction: An anal fissure is defined as a split in the mucosa extending from the anal verge towards the dentate line and most common proctologic symptom.
Nisar Ahmad Ansari   +2 more
doaj   +1 more source

Promising FDA-approved drugs with efflux pump inhibitory activities against clinical isolates of Staphylococcus aureus.

open access: yesPLoS ONE, 2022
Background and objectivesStaphylococcus aureus is an opportunistic pathogen that causes wide range of nosocomial and community-acquired infections which have spread worldwide leading to an urgent need for developing effective anti-staphylococcal agents ...
Safaa Abdel-Aal Mohamed Abdel-Karim   +3 more
doaj   +1 more source

Topical Lignocaine with Diltiazem or Glyceryltrinitrate for Paediatric Acute Anal Fissure: A Randomized Clinical Trial

open access: yesProceedings, 2021
Introduction: Anal fissure is a common problem in children, the exact etiology of which is unknown and it mostly presents with painful defecation and bleeding per rectum.
Mukhtiar Ahmed   +4 more
doaj   +1 more source

Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): an ambulance-based, randomised, sham-controlled, blinded, phase 3 trial

open access: yesThe Lancet, 2019
Summary Background High blood pressure is common in acute stroke and is a predictor of poor outcome; however, large trials of lowering blood pressure have given variable results, and the management of high blood pressure in ultra-acute stroke remains ...
Philip M Polly Craig S Jason P Evind Lesley Mark Timothy Bath Scutt Anderson Appleton Berge Cala Dixon Engl   +418 more
semanticscholar   +1 more source

A non-operative management of chronic anal fissure.

open access: yesJournal of Gandhara Medical and Dental Sciences, 2018
OBJECTIVES Assessment of efficacy of topical 0.2% glyceryl trinitrate ointment in the treatment of chronic anal fissure. PATIENTS AND METHODS A prospective study was carried out at surgical outpatient department Town Teaching Hospital from January 2017 ...
Azhar Shah
doaj   +1 more source

TRPA1/NOX in the soma of trigeminal ganglion neurons mediates migraine-related pain of glyceryl trinitrate in mice

open access: yesBrain : a journal of neurology, 2018
Glyceryl trinitrate administration causes prolonged mechanical allodynia in rodents, which correlates temporally with delayed migraine attacks in patients. Marone et al. show that the allodynia is mediated by TRPA1 activation in cell bodies of trigeminal
I. Marone   +10 more
semanticscholar   +1 more source

Prehospital Transdermal Glyceryl Trinitrate for Ultra-Acute Intracerebral Hemorrhage

open access: yesStroke, 2019
Supplemental Digital Content is available in the text.
P. Bath   +26 more
semanticscholar   +1 more source

Chronic snus use in healthy males alters endothelial function and increases arterial stiffness.

open access: yesPLoS ONE, 2022
BackgroundSnus usage is commonly touted as a safer alternative to cigarette smoking. However, recent studies have demonstrated possible adverse cardiovascular effects in chronic snus users.
Lukasz Antoniewicz   +6 more
doaj   +3 more sources

COMPARISON OF HEALING RATE OF ANAL FISSURE WITH 0.2% GLYCERYL TRINITRATE OINTMENT VERSUS 2% NIFEDIPINE OINTMENT

open access: yesPakistan Armed Forces Medical Journal, 2020
Objective: To compare the efficacy of topical 0.2% glyceryl trinitrate (GTN) ointment with 2% Nifedipine ointment in healing of anal fissure. Study Design: Quasi experimental study.
Usman Asghar   +4 more
doaj   +2 more sources

Reduced perfusion in systemic sclerosis digital ulcers (both fingertip and extensor) can be increased by topical application of glyceryl trinitrate

open access: yesMicrovascular Research, 2017
Objectives In patients with systemic sclerosis (SSc), fingertip digital ulcers (DUs) are believed to be ischaemic, and extensor surface DUs a result of mechanical factors/microtrauma.
Michael Hughes   +9 more
semanticscholar   +1 more source

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