Results 181 to 190 of about 192,952 (216)

Changes in Muscle Strength Following Semaglutide Treatment in Adults: A Systematic Review With Meta‐Analysis of Handgrip Strength

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To systematically review and quantitatively synthesize within‐group changes in skeletal muscle strength following semaglutide treatment in adults. Materials and Methods This PRISMA 2020 systematic review was registered in PROSPERO (CRD420251185935).
Luís Guilherme Machado, Pedro Henrique Siedschlag Schmidt, Guido Tasca Petroski, Geraldo Lucas Lopes Costa, Letícia Vieira dos Santos Ribeiro, João Victor Ramos Da Cruz, Graziela De Luca Canto, Alexandre Hohl, Marcelo Fernando Ronsoni, Simone van de Sande‐Lee   +9 more
wiley   +1 more source

Statement of Retraction. Shuangxi Wang, Jian Xu, Ping Song, Benoit Viollet, and Ming-Hui Zou. In Vivo Activation of AMP-Activated Protein Kinase Attenuates Diabetes-Enhanced Degradation of GTP Cyclohydrolase I. Diabetes 2009;58:1893-1901. DOI: 10.2337/db09-0267. PMID: 19528375. PMCID: PMC2712774. [PDF]

Diabetes
American Diabetes Association.
europepmc   +1 more source

1H NMR metabolomics and lipidomics analysis of neutrophils reveals biomarkers of ageing, inflammageing and frailty

The FEBS Journal, EarlyView.
Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah, Grace Filbertine, Lucy Gill, Asangaedem Akpan, Marie M. Phelan, Helen Louise Wright   +5 more
wiley   +1 more source

Rab10 Promotes Atlastin-Mediated Endoplasmic Reticulum Membrane Fusion. [PDF]

FASEB J
Kim M, Na K, Kim H, Jang E, Yoon SY, Lee C, Jun Y.   +6 more
europepmc   +1 more source

RNF13 regulates the endolysosomal pathway through interaction with the small GTPase Arl8B

The FEBS Journal, EarlyView.
The E3 ubiquitin ligase RNF13 functions as a regulatory scaffold, organizing Arl8B‐dependent complexes and tuning downstream signaling that controls endolysosomal organization and trafficking. In this model, wild‐type RNF13 associates with Arl8B on endolysosomes, whereas Arl8B (E22D/F55A) or RNF13 (L244A) variants weaken complex assembly, potentially ...
Audrey M. Sénécal, Valérie C. Cabana, Antoine Y. Bouchard, Laurent Cappadocia, Marc P. Lussier   +4 more
wiley   +1 more source

New Biochemical Insights into RIT GTPases Regulation and Membrane Interactions. [PDF]

Cells
Mirzaiebadizi A, Bazgir F, Mosaddeghzadeh N, Pudewell S, Kazemein Jasemi NS, Dvorsky R, Ahmadian MR.   +6 more
europepmc   +1 more source

Epigenetic control of cellular plasticity in breast cancer progression

The FEBS Journal, EarlyView.
Cancer cells undergo cell state transitions, termed plasticity, driving cancer progression and dictating therapeutic response. We define breast cancer plasticity into four interconnected processes: (1) breast cancer stem cell fates, (2) epithelial‐to‐mesenchymal transition, (3) maintenance of luminal identity, and (4) acquisition of therapeutic ...
Ellie J. Massey, Elizabeth Podleszanski, William J. Muller   +2 more
wiley   +1 more source

The Role of KRAS in Non-Small Cell Lung Cancer: From Molecular Background to Precision Medicine. [PDF]

Int J Mol Sci
Gaździcka J, Gołąbek K.
europepmc   +1 more source

KRAS signaling networks, mutational heterogeneity, and emerging therapeutic strategies for cancer treatment. [PDF]

Biomark Res
Jin S, Zhang Z, Liang F, Yang Y, Lu A, Liang C.   +5 more
europepmc   +1 more source

Tubulin flux at spastin-induced nanodamage sites regulates microtubule rescue frequency and EB1 lifetimes. [PDF]

Proc Natl Acad Sci U S A
Szczesna E, Spector JO, Sarbanes SL, Chen J, Szyk A, Roll-Mecak A.   +5 more
europepmc   +1 more source