BMC Bioinformatics, 2018 Background The endomembrane system, known as secretory pathway, is responsible for the synthesis and transport of protein molecules in cells. Therefore, genes involved in the secretory pathway are essential for the cellular development and function ...
Kumar Parijat Tripathi +2 more
doaj +1 more source
A mant-GDP Dissociation Assay to Compare the Guanine Nucleotide Binding Preference of Small GTPases
Bio-Protocol, 2021 Small GTPases are cellular switches that are switched on when bound to GTP and switched off when bound to GDP. Different small GTPase proteins or those with mutations may bind to GTP or GDP with different relative affinities.
玉萍 tanyuping, Qingxiang Sun
doaj +1 more source
Green tea polyphenol-reduced graphene oxide: derivatisation, reduction efficiency, reduction mechanism and cytotoxicity [PDF]
, 2014 This paper reports on the derivatisation, reduction efficiency, reduction mechanism and cytotoxicity of green tea polyphenol-reduced graphene oxide (GTP-RGO).
Abdullah, M. F. +2 more
core +2 more sources
Long-Term Cumulative Exposure to High γ-Glutamyl Transferase Levels and the Risk of Cardiovascular Disease: A Nationwide Population-Based Cohort Study [PDF]
Endocrinology and Metabolism, 2023 Background Elevated γ-glutamyl transferase (γ-GTP) levels are associated with metabolic syndrome. We investigated the association of cumulative exposure to high γ-GTP with the risk of cardiovascular disease (CVD) in a large-scale population.
Han-Sang Baek +7 more
doaj +1 more source
The chloroplast import receptor Toc34 functions as preprotein-regulated GTPase [PDF]
, 2002 Toc34 is a protein of the chloroplast outer envelope membrane that acts as receptor for preproteins containing a transit sequence. The recognition of preproteins by Toc34 is regulated by GTP binding and phosphorylation.
Hörth, P. +5 more
core +1 more source
Synthesis and Effect of Conformationally Locked Carbocyclic Guanine Nucleotides on Dynamin
Biomolecules, 2022 Guanine nucleotides can flip between a North and South conformation in the ribose moiety. To test the enzymatic activity of GTPases bound to nucleotides in the two conformations, we generated methanocarba guanine nucleotides in the North or South ...
Kiran S. Toti +4 more
doaj +1 more source
A guanosine 5′-triphosphate-dependent protein kinase is localized in the outer envelope membrane of pea chloroplasts [PDF]
, 1988 A guanosine 5-triphosphate (GTP)-dependent protein kinase was detected in preparations of outer chloroplast envelope membranes of pea (Pisum sativum L.) chloroplasts.
A.M. Edelman +34 more
core +1 more source
Reciprocal regulation of PKA and rac signaling [PDF]
, 2013 Activated G protein-coupled receptors (GPCRs) and receptor tyrosine kinases relay extracellular signals through spatial and temporal controlled kinase and GTPase entities.
A. Riml +47 more
core +1 more source
Frontiers in Earth Science, 2022 Three dimensional (3D) geological model is frequently used to represent the geological conditions of the subsurface. The generalized triangular prism (GTP) model designed for borehole sampling data is a spatial data model that could retain the internal ...
Liming Sun +5 more
doaj +1 more source
Dynamics of Microtubule Growth and Catastrophe [PDF]
, 2007 We investigate a simple model of microtubule dynamics in which a microtubule evolves by: (i) attachment of guanosine triphosphate (GTP) to its end at rate lambda, (ii) GTP converting irreversibly to guanosine diphosphate (GDP) at rate 1, and (iii ...
Antal, T. +4 more
core +1 more source