Results 11 to 20 of about 192,952 (216)
MacroH2A histone variants have functions in differentiation, somatic cell reprogramming and cancer. However, at present, it is not clear how macroH2As affect gene regulation to exert these functions.
Sarah Hurtado-Bagès +8 more
doaj +1 more source
Adaptive smooth building method for 3D geological model based on geometric subdivision
The generalized triangular prism (GTP) voxel designed for the borehole data is the commonly method in the geological modelling, and it can be used to build the 3D solid geological model to express the stratigraphic space through the adjacent GTP voxel ...
SUN Liming 1, LIU Yushan 1, ZHANG Ruizhuo 2, YANG Yujian 3, YAN Jun 1
doaj +1 more source
The Gutong Patch (GTP) is common in clinical practice for bone diseases. This study compared the efficacy and safety of GTP and nonsteroidal anti-inflammatory drugs (NSAIDs) for KOA patients from 35 medical centers assigned to GTP, selective COX-2 ...
Yingjie Wang +5 more
doaj +1 more source
Long-Term Cumulative Exposure to High γ-Glutamyl Transferase Levels and the Risk of Cardiovascular Disease: A Nationwide Population-Based Cohort Study [PDF]
Background Elevated γ-glutamyl transferase (γ-GTP) levels are associated with metabolic syndrome. We investigated the association of cumulative exposure to high γ-GTP with the risk of cardiovascular disease (CVD) in a large-scale population.
Han-Sang Baek +7 more
doaj +1 more source
Innovative Approach Reveals How Receptors Control G Protein State Equilibria [PDF]
Using conformational specific trFRET biosensors of the Gi protein (depicted at the bottom), the authors show that receptor activation can not only release GDP from the inactive G protein, but can also release GTP from the activated G protein, leading to the reformation of the RG ternary complex.
Bouyssou A +12 more
europepmc +2 more sources
A mant-GDP Dissociation Assay to Compare the Guanine Nucleotide Binding Preference of Small GTPases
Small GTPases are cellular switches that are switched on when bound to GTP and switched off when bound to GDP. Different small GTPase proteins or those with mutations may bind to GTP or GDP with different relative affinities.
玉萍 tanyuping, Qingxiang Sun
doaj +1 more source
Synthesis and Effect of Conformationally Locked Carbocyclic Guanine Nucleotides on Dynamin
Guanine nucleotides can flip between a North and South conformation in the ribose moiety. To test the enzymatic activity of GTPases bound to nucleotides in the two conformations, we generated methanocarba guanine nucleotides in the North or South ...
Kiran S. Toti +4 more
doaj +1 more source
Three dimensional (3D) geological model is frequently used to represent the geological conditions of the subsurface. The generalized triangular prism (GTP) model designed for borehole sampling data is a spatial data model that could retain the internal ...
Liming Sun +5 more
doaj +1 more source
This paper elucidates a close connection between two well-known facts that until now have seemed independent: (i) the quality control (“proofreading”) of the emerging amino acid sequence, occurring during the normal, elongation-factor ...
Alexei V. Finkelstein
doaj +1 more source
Probiotic shelf life, antioxidant, sensory, physical and chemical properties of yogurts produced with lactobacillus acidophilus and green tea powder [PDF]
The aim of the present study was to determine the effects of the addition of green tea powder (GTP) in the production of yogurt on survival of Lactobacillus acidophilus (P) and the yogurt properties. Four yogurt groups (yogurt without P and GTP, Control,
Songül ÇAKMAKÇI +7 more
doaj +1 more source

