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Crystal structure of the class V GTP-binding RNA aptamer bound to its ligand: GTP recognition by a topologically complex intermolecular G-quadruplex. [PDF]
Stafflinger H +10 more
europepmc +1 more source
Pan-KRAS inhibition: unlocking broad-spectrum targeted therapy for <i>KRAS</i>-mutant cancers. [PDF]
Feng J, Xiao X, Lian Z, Zhang A, Pang X.
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Monitoring cellular Guanosine triphosphate (GTP) and GTP associated proteins
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Physiological Reviews, 2001
Small GTP-binding proteins (G proteins) exist in eukaryotes from yeast to human and constitute a superfamily consisting of more than 100 members. This superfamily is structurally classified into at least five families: the Ras, Rho, Rab, Sar1/Arf, and Ran families.
Y, Takai, T, Sasaki, T, Matozaki
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Small GTP-binding proteins (G proteins) exist in eukaryotes from yeast to human and constitute a superfamily consisting of more than 100 members. This superfamily is structurally classified into at least five families: the Ras, Rho, Rab, Sar1/Arf, and Ran families.
Y, Takai, T, Sasaki, T, Matozaki
openaire +2 more sources
Regulation of GTP biosynthesis
Advances in Enzyme Regulation, 1992In the regulation of GTP biosynthesis, complex interactions are observed. A major factor is the behavior of the activity of IMPDH, the rate-limiting enzyme of de novo GTP biosynthesis, and the activity of GPRT, the salvage enzyme of guanylate production. The activities of GMP synthase, GMP kinase and nucleoside-diphosphate kinase are also relevant.
G, Weber +4 more
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Annual Review of Cell and Developmental Biology, 2013
Shape changes and topological remodeling of membranes are essential for the identity of organelles and membrane trafficking. Although all cellular membranes have common features, membranes of different organelles create unique environments that support specialized biological functions.
James A, McNew +4 more
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Shape changes and topological remodeling of membranes are essential for the identity of organelles and membrane trafficking. Although all cellular membranes have common features, membranes of different organelles create unique environments that support specialized biological functions.
James A, McNew +4 more
openaire +2 more sources

