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Interaction of liver plasma membranes and GTP with GTP hydrolysis
Biochemical and Biophysical Research Communications, 1973Abstract [ 14 C]GTP or a metabolic product of GTP binds to liver membranes. Less label was associated with membranes when membranes were incubated with increasing concentrations of carrier GTP; ATP did not displace the label. Chromatography of extracted incubation mixtures of [ 14 C]GTP and membranes revealed that over 96% of the nucleotide was ...
N I, Swislocki +2 more
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GDP/GTP Exchange Proteins for Small GTP-Binding Proteins
1993There is a superfamily of small GTP-binding proteins in which more than forty members are included (Bourne et al. 1991; Hall 1990; Takai et al. 1992). They exhibit GDP/GTP-binding and GTPase activities and have two interconvertible forms: GDP-bound inactive and GTP-bound active forms (Fig. 1).
Y. Takai +3 more
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Current Opinion in Structural Biology, 1991
Abstract There has been much progress this year in characterizing the complex series of post-translational modifications important for GTP-binding protein function. In addition, the long-awaited molecular characterization of a G protein that regulates phospholipase C activity has been reported.
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Abstract There has been much progress this year in characterizing the complex series of post-translational modifications important for GTP-binding protein function. In addition, the long-awaited molecular characterization of a G protein that regulates phospholipase C activity has been reported.
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Expression cloning to identify monomeric GTP-binding proteins by GTP overlay
2001Publisher Summary More than 70 small Ras-related GTP-binding proteins have been identified and additional members of the family continue to be discovered. The majority of these proteins have been isolated by screening genomic or cDNA libraries at low stringency with oligonucleotide mixes corresponding to the conserved guanine nucleotide-binding ...
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2019
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