Results 21 to 30 of about 4,611 (70)
Proteomic Analysis of Stage‐II Breast Cancer from Formalin‐Fixed Paraffin‐Embedded Tissues
BioMed Research International, Volume 2016, Issue 1, 2016., 2016 Breast cancer is the most frequently occurring disease among women worldwide. The early stage of breast cancer identification is the key challenge in cancer control and prevention procedures. Although gene expression profiling helps to understand the molecular mechanism of diseases or disorder in the living system, gene expression pattern alone is not ...
Naif Abdullah Al-Dhabi +9 more
wiley +1 more source
The Proteome and Lipidome of Thermococcus kodakarensis across the Stationary Phase
Archaea, Volume 2016, Issue 1, 2016., 2016 The majority of cells in nature probably exist in a stationary‐phase‐like state, due to nutrient limitation in most environments. Studies on bacteria and yeast reveal morphological and physiological changes throughout the stationary phase, which lead to an increased ability to survive prolonged nutrient limitation.
Emma J. Gagen +5 more
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Enzymes
British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +31 more
wiley +1 more source
Cellular Metabolic Network Analysis: Discovering Important Reactions in Treponema pallidum
BioMed Research International, Volume 2015, Issue 1, 2015., 2015 T. pallidum, the syphilis‐causing pathogen, performs very differently in metabolism compared with other bacterial pathogens. The desire for safe and effective vaccine of syphilis requests identification of important steps in T. pallidum’s metabolism. Here, we apply Flux Balance Analysis to represent the reactions quantitatively. Thus, it is possible to
Xueying Chen +3 more
wiley +1 more source
Metabolic Origin, Role and Fate of the Denaturant Guanidine
Microbial Biotechnology, Volume 18, Issue 11, November 2025.The origin of metabolic guanidine is largely a mystery. We suggest it is created when guanine‐containing nucleotides are oxidised by molecular oxygen instead of being broken down into urea as purines normally would. Guanidine may act as a signal to help cells control the level of reactive oxygen species.
Antoine Danchin +3 more
wiley +1 more source
Neural Plasticity, Volume 2015, Issue 1, 2015., 2015 In a phase I/IIa open‐label and nonrandomized controlled clinical trial, we sought to assess the safety and neurological effects of human neural stem/progenitor cells (hNSPCs) transplanted into the injured cord after traumatic cervical spinal cord injury (SCI).
Ji Cheol Shin +12 more
wiley +1 more source
MedComm, Volume 6, Issue 3, March 2025.The malignant transformation from chronic viral hepatitis to hepatocellular carcinoma (HCC) involves intricate interactions among viral, host, and environmental factors. Key drivers of this transformation include viral integration, genomic instability, epigenetic modifications, oxidative stress, gut microbiota dysbiosis, chronic inflammation, immune ...
Huimin Yuan +6 more
wiley +1 more source
Specific Proteins in Nontuberculous Mycobacteria: New Potential Tools
BioMed Research International, Volume 2015, Issue 1, 2015., 2015 Nontuberculous mycobacteria (NTM) have been isolated from water, soil, air, food, protozoa, plants, animals, and humans. Although most NTM are saprophytes, approximately one‐third of NTM have been associated with human diseases. In this study, we did a comparative proteomic analysis among five NTM strains isolated from several sources.
Patricia Orduña +5 more
wiley +1 more source
The enzymes of human diphosphoinositol polyphosphate metabolism
The FEBS Journal, Volume 281, Issue 1, Page 14-33, January 2014., 2014 This review covers the three classes of enzymes involved in the metabolism of diphosphoinositol polyphosphates – inositol hexakisphosphate kinases (IP6K), inositol hexakisphosphate and diphosphoinositol‐pentakisphosphate kinases (PPIP5K), and diphosphoinositol polyphosphate phosphohydrolases (DIPP).
Mark P. Thomas, Barry V. L. Potter
wiley +1 more source
Structural and mechanistic basis for the regulation of the chloroplast signal recognition particle by (p)ppGpp. [PDF]
FEBS LettZegarra V +7 more
europepmc +1 more source