Results 31 to 40 of about 5,048 (136)
The plant Nudix hydrolase family. [PDF]
, 2008 Nudix hydrolases are a family of proteins defined by a conserved amino-acid sequence GX(5)-EX(7)REUXEEXGU, where U is a hydrophobic residue. These enzymes are widely distributed among all classes of organisms and catalyze, with varying degrees of ...
Kraszewska, Elzbieta
core
Molecular Plant Pathology, Volume 27, Issue 2, February 2026.Erwinia amylovora infects apple blossoms by activating the T3SS, then spreads systemically via amylovoran‐mediated biofilms. Transitions between motile and sessile states are regulated by key two‐component systems and c‐di‐GMP. This review summarises infection biology, virulence factors, regulatory networks and evolutionary insights underlying fire ...
Dhirendra Niroula +3 more
wiley +1 more source
The Proteome and Lipidome of Thermococcus kodakarensis across the Stationary Phase
Archaea, Volume 2016, Issue 1, 2016., 2016 The majority of cells in nature probably exist in a stationary‐phase‐like state, due to nutrient limitation in most environments. Studies on bacteria and yeast reveal morphological and physiological changes throughout the stationary phase, which lead to an increased ability to survive prolonged nutrient limitation.
Emma J. Gagen +5 more
wiley +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Enzymes
British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +31 more
wiley +1 more source
Cellular Metabolic Network Analysis: Discovering Important Reactions in Treponema pallidum
BioMed Research International, Volume 2015, Issue 1, 2015., 2015 T. pallidum, the syphilis‐causing pathogen, performs very differently in metabolism compared with other bacterial pathogens. The desire for safe and effective vaccine of syphilis requests identification of important steps in T. pallidum’s metabolism. Here, we apply Flux Balance Analysis to represent the reactions quantitatively. Thus, it is possible to
Xueying Chen +3 more
wiley +1 more source
Comprehensive analysis of the HEPN superfamily: identification of novel roles in intra-genomic conflicts, defense, pathogenesis and RNA processing [PDF]
, 2013 BACKGROUND: The major role of enzymatic toxins that target nucleic acids in biological conflicts at all levels has become increasingly apparent thanks in large part to the advances of comparative genomics.
A Maxwell Burroughs +4 more
core +1 more source
Metabolic Origin, Role and Fate of the Denaturant Guanidine
Microbial Biotechnology, Volume 18, Issue 11, November 2025.The origin of metabolic guanidine is largely a mystery. We suggest it is created when guanine‐containing nucleotides are oxidised by molecular oxygen instead of being broken down into urea as purines normally would. Guanidine may act as a signal to help cells control the level of reactive oxygen species.
Antoine Danchin +3 more
wiley +1 more source
Neural Plasticity, Volume 2015, Issue 1, 2015., 2015 In a phase I/IIa open‐label and nonrandomized controlled clinical trial, we sought to assess the safety and neurological effects of human neural stem/progenitor cells (hNSPCs) transplanted into the injured cord after traumatic cervical spinal cord injury (SCI).
Ji Cheol Shin +12 more
wiley +1 more source
A Plasma Metabolomic Signature Involving Purine Metabolism in Human Optic Atrophy 1 (OPA1)-Related Disorders [PDF]
, 2018 Purpose: Dominant optic atrophy (DOA; MIM [Mendelian Inheritance in Man] 165500), resulting in retinal ganglion cell degeneration, is mainly caused by mutations in the optic atrophy 1 (OPA1) gene, which encodes a dynamin guanosine triphosphate (GTP)ase ...
A. Chevrollier +16 more
core +2 more sources
MedComm, Volume 6, Issue 3, March 2025.The malignant transformation from chronic viral hepatitis to hepatocellular carcinoma (HCC) involves intricate interactions among viral, host, and environmental factors. Key drivers of this transformation include viral integration, genomic instability, epigenetic modifications, oxidative stress, gut microbiota dysbiosis, chronic inflammation, immune ...
Huimin Yuan +6 more
wiley +1 more source