Results 21 to 30 of about 5,048 (136)

Miro1 Mediates the Neuroprotective Effects of Electroacupuncture Against Cerebral Ischemia-Reperfusion Injury in Mice

Journal of Integrative Neuroscience
Background: Cerebral ischemia-reperfusion injury (CIRI) is a severe neurological condition where restoring neuronal mitochondrial function critically impacts prognosis.
Huidan Lian, Yan Sun, Minyuan Zhang, Xiangying Gao, Junlu Wang, Qinxue Dai   +5 more
doaj   +1 more source

Alterations in gene expression in T1α null lung: a model of deficient alveolar sac development [PDF]

, 2006
BACKGROUND. Development of lung alveolar sacs of normal structure and size at late gestation is necessary for the gas exchange process that sustains respiration at birth.
Hinds, Anne, Millien, Guetchyn, Ramirez, Maria I., Spira, Avrum, Wang, Junling, Williams, Mary C.   +5 more
core   +3 more sources

Photoreceptor phosphodiesterase (PDE6): structure, regulatory mechanisms, and implications for treatment of retinal diseases [PDF]

, 2021
The photoreceptor phosphodiesterase (PDE6) is a member of large family of Class I phosphodiesterases responsible for hydrolyzing the second messengers cAMP and cGMP.
Cote, Rick H, Gupta, Richa, Irwin, Michael J, Wang, Xin   +3 more
core   +2 more sources

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes

British Journal of Pharmacology, Volume 176, Issue S1, Page S297-S396, December 2019., 2019
The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www ...
Stephen P H Alexander, Doriano Fabbro, Eamonn Kelly, Alistair Mathie, John A Peters, Emma L Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Adam J Pawson, Joanna L Sharman, Christopher Southan, Jamie A Davies, CGTP Collaborators, Annie Beuve, Detlev Boison, Peter Brouckaert, John C Burnett, Kathryn Burns, Carmen Dessauer, Andreas Friebe, John Garthwaite, Jürg Gertsch, Nuala Helsby, Angelo A Izzo, Doris Koesling, Michaela Kuhn, Rennolds Ostrom, Andreas Papapetropoulos, Lincoln R Potter, Nigel J Pyne, Susan Pyne, Michael Russwurm, Harald HHW Schmidt, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts   +39 more
wiley   +1 more source

The Many Facets of Sphingolipids in the Specific Phases of Acute Inflammatory Response

Mediators of Inflammation, Volume 2018, Issue 1, 2018., 2018
This review provides an overview on components of the sphingolipid superfamily, on their localization and metabolism. Information about the sphingolipid biological activity in cell physiopathology is given. Recent studies highlight the role of sphingolipids in inflammatory process.
Sabine Grösch, Alice V. Alessenko, Elisabetta Albi, Vinod K. Mishra   +3 more
wiley   +1 more source

Secretory pathway of trypanosomatid parasites [PDF]

, 2002
The Trypanosomatidae comprise a large group of parasitic protozoa, some of which cause important diseases in humans. These include Tryanosoma brucei (the causative agent of African sleeping sickness and nagana in cattle), Trypanosoma cruzi (the causative
McConville, Malcolm J., Mullin, Kylie A., Ilgoutz, Steven C., Teasdale, Rohan D.   +3 more
core   +1 more source

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Enzymes

British Journal of Pharmacology, Volume 174, Issue S1, Page S272-S359, December 2017., 2017
The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand ...
Stephen PH Alexander, Doriano Fabbro, Eamonn Kelly, Neil V Marrion, John A Peters, Elena Faccenda, Simon D Harding, Adam J Pawson, Joanna L Sharman, Christopher Southan, Jamie A Davies, CGTP Collaborators   +11 more
wiley   +1 more source

Biofilms and cyclic di-GMP (c-di-GMP) signaling: lessons from Pseudomonas aeruginosa and other bacteria

, 2016
The cyclic di-GMP (c-di-GMP) second messenger represents a signaling system that regulates many bacterial behaviors and is of key importance for driving the lifestyle switch between motile loner cells and biofilm formers.
Filloux, A, Valentini, M
core   +2 more sources

Gap Analysis of Metabolic Conversions of Off‐Flavors and Antinutrients in Plant‐Based Substrates

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT To drastically reduce the carbon footprint of the food production chain, a major shift towards alternatives to conventional meat and dairy products is required. The use of plant‐based proteins is a promising route, but it also comes with challenges: Plant‐based proteins often contain antinutritional factors and off‐flavors, which can ...
Robin I. Kuijpers, Isabel O. de Moya Clark, Tomás Cavaco, Vivian Nemanič, Beatrice Tagliabue, Ainhoa Valero‐Abad, Wiebe M. Wennekers, Mengqiu Zhang, Koen Van Zwet, Sanne Abeln, Sofia Moco, Caroline E. Paul, Halima Mouhib, Richard A. Notebaart, Eddy J. Smid, Bas Teusink, Herwig Bachmann   +16 more
wiley   +1 more source

Proteomic Analysis of Stage‐II Breast Cancer from Formalin‐Fixed Paraffin‐Embedded Tissues

BioMed Research International, Volume 2016, Issue 1, 2016., 2016
Breast cancer is the most frequently occurring disease among women worldwide. The early stage of breast cancer identification is the key challenge in cancer control and prevention procedures. Although gene expression profiling helps to understand the molecular mechanism of diseases or disorder in the living system, gene expression pattern alone is not ...
Naif Abdullah Al-Dhabi, Srisesharam Srigopalram, Soundharrajan Ilavenil, Young Ock Kim, Paul Agastian, Rajasekhar Baaru, Kannan Balamurugan, Ki Choon Choi, Mariadhas Valan Arasu, Gagan Deep   +9 more
wiley   +1 more source