Results 31 to 40 of about 5,029 (135)

Alterations in gene expression in T1α null lung: a model of deficient alveolar sac development [PDF]

open access: yes, 2006
BACKGROUND. Development of lung alveolar sacs of normal structure and size at late gestation is necessary for the gas exchange process that sustains respiration at birth.
Millien, Guetchyn   +5 more
core   +2 more sources

Photoreceptor phosphodiesterase (PDE6): structure, regulatory mechanisms, and implications for treatment of retinal diseases [PDF]

open access: yes, 2021
The photoreceptor phosphodiesterase (PDE6) is a member of large family of Class I phosphodiesterases responsible for hydrolyzing the second messengers cAMP and cGMP.
Cote, Rick H   +3 more
core   +2 more sources

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes

open access: yesBritish Journal of Pharmacology, Volume 176, Issue S1, Page S297-S396, December 2019., 2019
The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www ...
Stephen P H Alexander   +39 more
wiley   +1 more source

The Many Facets of Sphingolipids in the Specific Phases of Acute Inflammatory Response

open access: yesMediators of Inflammation, Volume 2018, Issue 1, 2018., 2018
This review provides an overview on components of the sphingolipid superfamily, on their localization and metabolism. Information about the sphingolipid biological activity in cell physiopathology is given. Recent studies highlight the role of sphingolipids in inflammatory process.
Sabine Grösch   +3 more
wiley   +1 more source

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Enzymes

open access: yesBritish Journal of Pharmacology, Volume 174, Issue S1, Page S272-S359, December 2017., 2017
The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand ...
Stephen PH Alexander   +11 more
wiley   +1 more source

Proteomic Analysis of Stage‐II Breast Cancer from Formalin‐Fixed Paraffin‐Embedded Tissues

open access: yesBioMed Research International, Volume 2016, Issue 1, 2016., 2016
Breast cancer is the most frequently occurring disease among women worldwide. The early stage of breast cancer identification is the key challenge in cancer control and prevention procedures. Although gene expression profiling helps to understand the molecular mechanism of diseases or disorder in the living system, gene expression pattern alone is not ...
Naif Abdullah Al-Dhabi   +9 more
wiley   +1 more source

The plant Nudix hydrolase family. [PDF]

open access: yes, 2008
Nudix hydrolases are a family of proteins defined by a conserved amino-acid sequence GX(5)-EX(7)REUXEEXGU, where U is a hydrophobic residue. These enzymes are widely distributed among all classes of organisms and catalyze, with varying degrees of ...
Kraszewska, Elzbieta
core  

Virulence Regulation and Lifestyle Transitions: The Role of c‐di‐GMP and Two‐Component Systems in Erwinia amylovora and Their Evolutionary Context Within Enterobacterales

open access: yesMolecular Plant Pathology, Volume 27, Issue 2, February 2026.
Erwinia amylovora infects apple blossoms by activating the T3SS, then spreads systemically via amylovoran‐mediated biofilms. Transitions between motile and sessile states are regulated by key two‐component systems and c‐di‐GMP. This review summarises infection biology, virulence factors, regulatory networks and evolutionary insights underlying fire ...
Dhirendra Niroula   +3 more
wiley   +1 more source

The Proteome and Lipidome of Thermococcus kodakarensis across the Stationary Phase

open access: yesArchaea, Volume 2016, Issue 1, 2016., 2016
The majority of cells in nature probably exist in a stationary‐phase‐like state, due to nutrient limitation in most environments. Studies on bacteria and yeast reveal morphological and physiological changes throughout the stationary phase, which lead to an increased ability to survive prolonged nutrient limitation.
Emma J. Gagen   +5 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +31 more
wiley   +1 more source

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