BIOLOGICAL FUNCTIONS OF THE NOVEL LYSOPHOSPHATIDIC ACID (LPA) RECEPTOR, LPA\u3csub\u3e4\u3c/sub\u3e/p2y9/GPR23 [PDF]
Lysophosphatidic acid (LPA), a naturally occurring phospholipid present in serum and malignant effusions, elicits diverse biological functions through binding and activating specific cell surface G-protein coupled receptors.
Lee, Peilun
core +1 more source
Platform-directed allostery and quaternary structure dynamics of SAMHD1 catalysis [PDF]
SAMHD1 regulates cellular nucleotide homeostasis, controlling dNTP levels by catalysing their hydrolysis into 2’-deoxynucleosides and triphosphate. In differentiated CD4+ macrophage and resting T-cells SAMHD1 activity results in the inhibition of HIV-1 ...
Acton, Oliver J. +9 more
core +2 more sources
Die Rolle der Phospholipase D2 in der agonisten-induzierten Endozytose von Opioid Rezeptoren [PDF]
von Liquan ...
Yang, Liquan
core +1 more source
A 16.7 kb deletion in \u3ci\u3eSipa1l3\u3c/i\u3e is associated with juvenile cataract in mice [PDF]
Congenital or juvenile cataract is a disease condition in which opacification of the lenses is present at birth or manifests early in life. It has been attributed to different monogenic factors with a high degree of heterogeneity and is often studied ...
Abebe, Marytza D. +9 more
core +1 more source
Bisphosphonate Modulates Cementoblast Behavior In Vitro [PDF]
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/142297/1/jper1890 ...
Benford HL +16 more
core +1 more source
Structural and Mechanistic Analysis of (p)ppGpp Synthetases [PDF]
The ability of microorganisms to survive under a large variety and rapidly changing environmental conditions is one of their most outstanding features and allowed them to establish within all niches of our planet.
Steinchen, Wieland
core +1 more source
Duplicated DNA Damage-Inducible Genes DDI2/DDI3 in Budding Yeast Saccharomyces cerevisiae Encodes a Functional Cyanamide Hydratase [PDF]
In a yeast genome-wide microarray analysis, two Saccharomyces cerevisiae open reading frames YFL061w and YNL335w displayed the highest fold levels of induction after methyl methanesulfonate (MMS) treatment, a typical DNA damaging agent.
Li, Jia 1984-
core
Development of Bifunctional Lysophosphatidic Acid & Lysophosphatidylcholine Activity Probes to Characterize Their Specific Binding Protein Receptors [PDF]
Lysophosphatidic acid (LPA) and lysophosphatidylcholine (LPC) activity has been found to be dysregulated in cancer cells and therefore is a crucial target for research.
Nandal, Ritu
core +1 more source
Development of soft and rigid membrane nanotemplates for the mechanistic analysis of Dynamin I action on curved surfaces [PDF]
141 p.En los últimos años se ha ido desvelando el rol activo de la curvaturade membrana en los procesos de reorganización de membranas celulares. Lamayoría de las membranas celulares presentan una cierta curvatura; dichacurvatura es moderada en los casos
Rodríguez Hortelano, Eva
core

