Results 51 to 60 of about 5,029 (135)

BIOLOGICAL FUNCTIONS OF THE NOVEL LYSOPHOSPHATIDIC ACID (LPA) RECEPTOR, LPA\u3csub\u3e4\u3c/sub\u3e/p2y9/GPR23 [PDF]

open access: yes, 2008
Lysophosphatidic acid (LPA), a naturally occurring phospholipid present in serum and malignant effusions, elicits diverse biological functions through binding and activating specific cell surface G-protein coupled receptors.
Lee, Peilun
core   +1 more source

Platform-directed allostery and quaternary structure dynamics of SAMHD1 catalysis [PDF]

open access: yes
SAMHD1 regulates cellular nucleotide homeostasis, controlling dNTP levels by catalysing their hydrolysis into 2’-deoxynucleosides and triphosphate. In differentiated CD4+ macrophage and resting T-cells SAMHD1 activity results in the inhibition of HIV-1 ...
Acton, Oliver J.   +9 more
core   +2 more sources

A 16.7 kb deletion in \u3ci\u3eSipa1l3\u3c/i\u3e is associated with juvenile cataract in mice [PDF]

open access: yes, 2017
Congenital or juvenile cataract is a disease condition in which opacification of the lenses is present at birth or manifests early in life. It has been attributed to different monogenic factors with a high degree of heterogeneity and is often studied ...
Abebe, Marytza D.   +9 more
core   +1 more source

Bisphosphonate Modulates Cementoblast Behavior In Vitro [PDF]

open access: yes, 2005
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/142297/1/jper1890 ...
Benford HL   +16 more
core   +1 more source

Structural and Mechanistic Analysis of (p)ppGpp Synthetases [PDF]

open access: yes, 2017
The ability of microorganisms to survive under a large variety and rapidly changing environmental conditions is one of their most outstanding features and allowed them to establish within all niches of our planet.
Steinchen, Wieland
core   +1 more source

Duplicated DNA Damage-Inducible Genes DDI2/DDI3 in Budding Yeast Saccharomyces cerevisiae Encodes a Functional Cyanamide Hydratase [PDF]

open access: yes, 2016
In a yeast genome-wide microarray analysis, two Saccharomyces cerevisiae open reading frames YFL061w and YNL335w displayed the highest fold levels of induction after methyl methanesulfonate (MMS) treatment, a typical DNA damaging agent.
Li, Jia 1984-
core  

Development of Bifunctional Lysophosphatidic Acid & Lysophosphatidylcholine Activity Probes to Characterize Their Specific Binding Protein Receptors [PDF]

open access: yes, 2011
Lysophosphatidic acid (LPA) and lysophosphatidylcholine (LPC) activity has been found to be dysregulated in cancer cells and therefore is a crucial target for research.
Nandal, Ritu
core   +1 more source

Development of soft and rigid membrane nanotemplates for the mechanistic analysis of Dynamin I action on curved surfaces [PDF]

open access: yes, 2015
141 p.En los últimos años se ha ido desvelando el rol activo de la curvaturade membrana en los procesos de reorganización de membranas celulares. Lamayoría de las membranas celulares presentan una cierta curvatura; dichacurvatura es moderada en los casos
Rodríguez Hortelano, Eva
core  

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