Results 171 to 180 of about 4,383 (215)
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Cyclovinylogues of Guanethidine
Archiv der Pharmazie, 1988AbstractThree isomeric cyclovinylogues of guanethidine are described in which a benzene ring is interposed between the methylene groups of the basic chain. The pharmacological properties of the products were investigated.
Valenti P +5 more
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Guanethidine in Hyperthyroidism
JAMA, 1964Guanethidine sulfate has been administered to 90 patients with overt hyperthyroidism. By virtue of its potent and unique sympatholytic effects it ameliorates promptly and effectively those signs and symptoms of thyrotoxicosis due to sympathetic hyperactivity without affecting the function of the thyroid gland.
S S, WALDSTEIN +3 more
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Drug interactions with guanethidine
Clinical Pharmacology & Therapeutics, 1973The effect of a single oral dose of tripelennamine, 100 mg., methyldopa, 500 mg., d‐amphetamine, 10 mg., amitriptyline, 50 mg., or prochlorperazine, 25 mg., on the blood pressures of hypertensive patients treated chronically with guanethidine was measured half‐hourly for 8 hours.
K F, Ober, R I, Wang
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Metabolic Effects of Guanethidine
Pharmacology, 2008The metabolic effects of guanethidine were studied in anaesthetized rats. The drug (20 and 40 mg/kg body weight) produced a significant rise in serum free fatty acids (FFA) without significant changes in serum glucose and lactate levels. Epididymal fat pads excised from guanethidine-treated (20 mg/kg body weight) rats and incubated in vitro, exhibited ...
Z H, Hussein, M H, Ayobe, N A, Damarawy
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Guanadrel and guanethidine in hypertension
Clinical Pharmacology & Therapeutics, 1970A modified double‐blind study was carried out in 40 patients with moderate to severe hypertensive disease. Twenty patients were treated with guanadrel in oral doses of 30 to 400 mg. daily for 17 weeks; the other 20 patients were treated with guanethidine in oral doses of 10 to 200 mg. daily for 14 weeks.
D K, Bloomfield, J L, Cangiano
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IONTOPHORESIS OF GUANETHIDINE IN MAN
Australian Journal of Experimental Biology and Medical Science, 1964SummaryIn a search for more efficient methods of treatment of peripheral vascular disease, the technique of iontophoresis of guanethidine into fingers of healthy male volunteers has been investigated. The effects of this drug on heat output in 10 subjects and on sympathetic vasoconstrictor reflexes in five subjects were measured by calorimetry ...
I E, DELALANDE +3 more
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Antagonism of Guanethidine by Chlorpromazine
American Journal of Psychiatry, 1973Chlorpromazine was found to reverse the antihypertensive effects of guanethidine six times in use with four moderately or severely hypertensive psychiatric patients. Haloperidol and thiothixene caused similar effects. It is postulated that this drug-drug interaction occurs because chlorpromazine blocks the neuronal amine-guanethidine uptake pump ...
D S, Janowsky +3 more
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