Results 241 to 250 of about 133,980 (384)

Cyclic guanidines. XV. Synthesis and biological activities of (substituted phenyl)-imidazo(1,2-a)imidazole derivatives.

, 1985
Fumiyoshi Ishikawa, Masayuki Kitagawa, Yoshinari Satoh, J. SAEGUSA, Satoru Tanaka, Seiichi Shibamura, Tomomi Chiba   +6 more
openalex   +2 more sources

CSN6 Promotes Pancreatic Cancer Progression and Gemcitabine Resistance via Antagonizing DCAF1‐Mediated Ubiquitination of NPM1

Advanced Science, Volume 13, Issue 1, 5 January 2026.
COP9 signalosome subunit 6 (CSN6) promotes the auto‐ubiquitination and degradation of DDB1‐CUL4 associated factor 1 (DCAF1), thereby antagonizing DCAF1‐mediated ubiquitination of Nucleophosmin (NPM1). This stabilization of NPM1 enhances the ribosome biogenesis process and the translation of specific gemcitabine‐resistance proteins, ultimately driving ...
Yijing Zhang, Han Gao, Aiwen Tang, Haiwen Lyu, Zongmin Fan, Jiahui Guo, Yuzhi Wang, Hairong Yi, Qihao Pan, Haidan Luo, Baifu Qin, Boyu Zhang, Xiangqi Meng, Qingxin Liu, Mong‐Hong Lee   +14 more
wiley   +1 more source

Antimicrobial activity of a short guanidine mimic immobilised on contact lenses. [PDF]

J Mater Sci Mater Med
Sara M, Kuppusamy R, Enninful G, Suresh D, Vasilev K, Mackenzie D, Dehghani F, Hui A, Wong EHH, Yasir M, Kumar N, Willcox M.   +11 more
europepmc   +1 more source

Unfolding and aggregation-associated changes in the secondary structure ofD-glyceraldehyde-3-phosphate dehydrogenase during denaturation by guanidine hydrochloride as monitored by FTIR [PDF]

, 1997
Xiaofeng Li, Junmei Zhou
openalex   +1 more source

Multiscale 3D Whole Joint Cellular and Molecular Mapping Reveals Disease‐Specific Neurovascular Plasticity Underlying the Structure‐Pain Relationship

Advanced Science, Volume 13, Issue 1, 5 January 2026.
This study presents MUSIC, a novel immunostaining and clearing method coupled with large‐field light sheet microscopy, enabling 3D high‐resolution cellular and molecular mapping of intact musculoskeletal joints across species and joint types. Using joint degenerative and injury models, disease‐specific neurovascular alterations are uncovered, revealing
Peng Chen, Jiaxin Chai, Abirami Soundararajan, R. Glenn Hepfer, Benjamin Kheyfets, Jiaxin Hu, Ishraq Alshanqiti, Swarnalakshmi Raman, Ikue Tosa, Jun Tae Huh, Matthew Yee, Brooke J. Damon, Shangping Wang, Yu Shin Kim, Man‐Kyo Chung, Mildred C. Embree, Janice S. Lee, Tong Ye, Hai Yao   +18 more
wiley   +1 more source

Solid-Phase Synthesis of Guanine Derivatives with Four Diversity Elements via AgNO₃‑Mediated Guanidine Formation. [PDF]

ACS Omega
Moon J, Lee J, Lee H, Yoon G, Lee T.
europepmc   +1 more source

Rearrangement of 2-(2,5-Dioxopyrrolidin-1-yl)guanidine: An Efficient Synthesis and Structure of 3-(5-Amino-1H-1,2,4-triazol-3-yl)propanoic Acid and Derivatives

, 2010
Victor M. Chernyshev, А. В. Чернышева, З.А. Старикова   +2 more
openalex   +1 more source

The Crosstalk Between CRL5 and APC/C E3 Ligases Regulates Metastasis and Chemosensitivity of Cancer Cells

Advanced Science, Volume 13, Issue 3, 14 January 2026.
This study uncovers a previously unknown crosstalk between two major ubiquitin ligases, CRL5 and APC/C. The authors identify APC11 as a binding partner of CUL5, showing that their interaction regulates neddylation, substrate stability, and mitotic progression.
Danrui Cui, Ruirui Qu, Tianqi Li, Linchen Wang, Xiaoyu Chen, Shengpeng Shao, Xue Liang, Jun Xu, Yi Sun, Xiufang Xiong, Yongchao Zhao   +10 more
wiley   +1 more source

A 2nd-generation scalable synthesis of the HIV-1 entry inhibitor CJF-III-288 enabled by photoredox catalysis.

Chem Commun (Camb)
Nadraws JW, Pokle MS, Smith AB.
europepmc   +1 more source

A two-dimensional liquid chromatography method with optimized pretreatment for detection of guanidine compounds in animal liver and kidney. [PDF]

Food Chem X
Ning KM, Zhou Q, Yang RJ, Zhou YQ, Jiang JL, Li BE, Liu ZY.   +6 more
europepmc   +1 more source