Results 251 to 260 of about 133,980 (384)

Modular sub-monomeric cell-penetrating guanidine-rich peptoids – synthesis, assembly and biological evaluation

open access: gold, 2017
Étienne Marouseau   +6 more
openalex   +2 more sources

Nanoscopic Mapping of the Extracellular Space in Amyloid Plaque‐rich Cortex

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
The extracellular space and diffusion around amyloid plaques are examined using shadow imaging and single‐particle tracking. Increased diffusivity is found near plaques, extracellular matrix alterations, and plaque core penetrability that varies with amyloid phenotype.
Juan Estaún‐Panzano   +11 more
wiley   +1 more source

Gut proteome and microbiome alterations: Analysis of transverse colon samples from pathologically confirmed Alzheimer's disease patients

open access: yesAlzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) has been regarded as a brain‐first disorder. Emerging evidence suggests that the gut may influence central nervous system pathology, but the mechanisms remain unclear. METHODS We conducted a proteomic and microbial analysis of transverse colon samples from clinically and pathologically confirmed AD and ...
Qiwen Cheng   +6 more
wiley   +1 more source

Engineering of High‐Yield Recombinant Adeno‐Associated Virus Producer Plasmids

open access: yesBiotechnology Journal, Volume 21, Issue 1, January 2026.
Graphical Abstract and Lay Summary Recombinant adeno‐associated viruses (AAV) are important in gene therapy but their production may be impaired by non‐optimized gene design. In this study, the authors demonstrate that production was best when the AAV replicase gene was in a wild‐type configuration while the complexity of other genetic elements could ...
Marco T. Radukic   +10 more
wiley   +1 more source

Thermal Induced Changes in Cuticle and Cortex to Chemically Treated Hair

open access: yesBiopolymers, Volume 117, Issue 1, January 2026.
ABSTRACT The deterioration of the cuticle and cortex hair due to routine cosmetic practices has been identified as a primary factor contributing to undesirable changes in the esthetic qualities of hair. Chemical and physical treatments can cause significant damage to hair fibers.
C. R. R. C. Lima   +4 more
wiley   +1 more source

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