Results 261 to 270 of about 133,980 (384)

Intrinsically Fluorescent Nano‐Scaled Peptide Aggregates Upon Arginine to Citrulline Swap

Biotechnology and Bioengineering, Volume 123, Issue 1, Page 43-51, January 2026.
ABSTRACT The supramolecular assembly of short peptides into ordered structures offers promise for developing bio‐nanomaterials with diverse applications in drug delivery, electronics, and optical engineering. Intrinsic fluorescence of polypeptide aggregates is typically associated with delocalization of electron densities in dense hydrogen bonding ...
Nauman Nazeer, Anupama Ghimire, Jan K. Rainey, William D. Lubell, Brian D. Wagner, Marya Ahmed   +5 more
wiley   +1 more source

Downstream Process Intensification for AAV Purification by Affinity Chromatography Using Single Pass Tangential Flow Filtration

Biotechnology and Bioengineering, Volume 123, Issue 1, Page 174-185, January 2026.
ABSTRACT To enable adeno‐associated viral vectors (AAV) to achieve their maximum potential, next‐generation manufacturing processes must be developed to make gene therapies more affordable and accessible. This study focused on the design of two different intensified AAV downstream manufacturing processes at bench and pilot scale.
Akshay S. Chaubal, Ronny Horax, Christopher J. Yehl, S. Ranil Wickramasinghe, Xianghong Qian, Lu Wang, Andrew L. Zydney   +6 more
wiley   +1 more source

Aluminum Cations Stabilized by Hybrid N-Heterocyclic Imine Ligand as Catalysts for Guanidine Synthesis from Carbodiimides and Anilines. [PDF]

Chem Asian J
Chang TW, Hung YF, Lin WY, Leung TF.
europepmc   +1 more source

Mixture-Based Heterocyclic Combinatorial Positional Scanning Libraries: Discovery of Bicyclic Guanidines Having Potent Antifungal Activities against Candida albicans and Cryptococcus neoformans

, 1999
Sylvie E. Blondelle, Ema T. Crooks, John M. Ostresh, Richard A. Houghten   +3 more
openalex   +1 more source

Selection and Characterization of SARS‐CoV‐2 Spike Binding Clickmers

ChemBioChem, Volume 27, Issue 1, January 2026.
Split‐combine click‐systematic evolution of ligands by exponential enrichment against wild‐type SARS‐CoV‐2 spike glycoprotein yields benzofuran‐ and indole‐functionalized DNA aptamers (clickmers). These clickmers retain specific binding to multiple variants with nanomolar affinity, and the 31 nt indole‐functionalized truncate T2 retains binding to ...
Nima Moradzadeh, Anna Jonczyk, Anton Schmitz, Volkmar Fieberg, Laia Civit, Julián Valero, Michael Famulok, Günter Mayer   +7 more
wiley   +1 more source

Regulation on Dual Interfaces of QD with ETL and HTL by Guanidine-Based Ligands Enable High-Performance Blue Quantum Dot Light-Emitting Diodes with 24.3% External Quantum Efficiency. [PDF]

Adv Sci (Weinh)
Ren Y, Wang Y, Fang Y, Jiang X, Cheng K, Du Z.   +5 more
europepmc   +1 more source

A Stable Bioisostere of Ester‐Linked Ubiquitin Chains Enables Decoding of Protein Interactors

ChemBioChem, Volume 27, Issue 1, January 2026.
An ester‐to‐amide analog of an ester‐linked ubiquitin dimer is chemically synthesized through a convergent approach involving the sequential chemoselective ligation of three peptide fragments generated through Fmoc‐based solid‐phase peptide synthesis. The hydrolysis‐resistant ubiquitin dimer served as a chemical probe in the identification of potential
Yoshinori Taguchi, Takuya Tomita, Takuma Nishizawa, Dai Nakamura, Showmitra Saha, Takanori Oyoshi, Kohei Sato, Nobuyuki Mase, Yasushi Saeki, Tetsuo Narumi   +9 more
wiley   +1 more source

The Role of Mast Cells in Healing Purulent Wounds Using a Drug from the Polyhexamethylene Guanidine Group with the Antiseptic Polyhexanide: An Ultrastructural Study. [PDF]

Int J Mol Sci
Chekmareva I, Emaimo John A, Kostin A, Alekhnovich A, Volodkin A, Klabukov I, Baranovskii D, Shishkina V, Buchwalow I, Tiemann M, Atiakshin D.   +10 more
europepmc   +1 more source

The Structure of the Guanidine-II Riboswitch

Cell Chemical Biology, 2017
Lin Huang, Jia Wang, D. Lilley
semanticscholar   +1 more source

Expanding the Alkene‐Forming Capability of the Pseudomonas Savastanoi Ethylene‐Forming Enzyme

ChemCatChem, Volume 18, Issue 1, 15 January 2026.
Bump‐and‐hole studies on the Pseudomonas savastanoi ethylene‐forming enzyme (PsEFE) enable formation of low levels of alkene products other than ethylene from naturally occurring 2‐oxoglutarate derivatives. The results show that plants and/or microorganisms have potential for enzyme‐catalyzed production of propylene and 1‐butylene, potentially to exert
Siddhant Dhingra, Yihong Sun, Zhihong Zhang, Christopher J. Schofield, Lennart Brewitz   +4 more
wiley   +1 more source