Results 221 to 230 of about 201,610 (282)

Design, Mechanisms, and Applications of DNA‐Mediated Dynamically Reconfigurable Plasmonic Gold Nanostructures

Small Methods, EarlyView.
This review provides key principles of designing and synthesizing reconfigurable plasmonic gold nanostructures for generating and controlling physical, chemical, and biological properties and functions. The recent advances in the biological and materials applications of dynamically reconfigurable plasmonic gold nanostructures are also summarized ...
So Young Choi, Jieun Kim, Eun Ho Song, Eunhye Park, Jingrui Wu, Juyeon Yoo, Jwa‐Min Nam   +6 more
wiley   +1 more source

“Lock and Key”: Binding Behavior of Malachite Green and Functional Nucleic Acids and Their Multidimensional Applications

Small Structures, EarlyView.
The review comprehensively summarizes the binding behaviors and multidimensional applications of malachite green with diverse functional nucleic acids. By integrating structural mechanisms, comparative analysis, and application strategies across eight domains, it provides theoretical guidance and future perspectives for developing intelligent nucleic ...
Keren Chen, Yangzi Zhang, Qian Yang, Longjiao Zhu, Wentao Xu   +4 more
wiley   +1 more source

Insights on the phenology of the Asian longhorned tick (Haemaphysalis longicornis) using stored lipids

Insect Science, EarlyView.
Lipid analysis of field‐collected ticks unveiled a complex population structure and supports the potential for several stages to overwinter. Abstract The seasonality of Haemaphysalis longicornis in the United States comprises overlapping life stages in the spring and summer.
Matthew Bickerton, Julia González, Alvaro Toledo   +2 more
wiley   +1 more source

Methylome Profiling of a Deuterostome Invertebrate Using Oxford Nanopore Technology (ONT)

Molecular Ecology Resources, EarlyView.
ABSTRACT DNA methylation is crucial for genome regulation and provides key insights into the interaction between genetics and environmental factors, offering valuable perspectives for ecological research. However, knowledge of DNA methylation patterns in nonmodel invertebrates remains limited.
Sarah Lok Ting Kwong, Alyssa Maree Budd, Julia Yun‐Hsuan Hung, Cecilia Villacorta‐Rath, Sven Uthicke   +4 more
wiley   +1 more source

Brain DNA Methylation Atlas of AppNL‐G‐F Alzheimer's Disease Model Mice Across Age and Region Reveals Choline‐Induced Resilience

Aging Cell, EarlyView.
Brain DNA methylation drives abnormal gene expression in AppNL‐G‐F mice. Perinatal choline supplementation may promote resilience to synaptic dysfunction through modulation of DNA methylation. ABSTRACT Alzheimer's disease (AD) is the most common type of dementia.
Andre Krunic, Thomas A. Bellio, Benjamin Z. Cohen, Adam Labadorf, Thor D. Stein, Honghuang Lin, Tiffany J. Mellott, Jan K. Blusztajn   +7 more
wiley   +1 more source

Genotype‐by‐sex interaction analyses for alcohol use disorder across biobanks

Alcohol, Clinical and Experimental Research, EarlyView.
Alcohol use disorder (AUD) differs by sex in prevalence and clinical features, yet genetic studies on these differences are limited. Using genome‐wide genotype‐by‐sex interaction analyses in over 1 million participants from the Million Veteran Program and UK Biobank, we identified four significant loci with sex‐specific effects on AUD risk.
Hang Zhou, Lu Wang, Zhongzheng Mao, P. J. Michael Deans, Rachel L. Kember, Qingyu Chen, Yasmin Zakiniaeiz, Robert Kohler, MacKenzie R. Peltier, Terril L. Verplaetse, VA Million Veteran Program, Marc N. Potenza, Kristen J. Brennand, Amy C. Justice, Henry R. Kranzler, Joel Gelernter, Sherry A. McKee, Sumitra Muralidhar, Jennifer Moser, Jennifer E. Deen, Philip S. Tsao, Sumitra Muralidhar, J. Michael Gaziano, Elizabeth Hauser, Amy Kilbourne, Michael Matheny, Dave Oslin, Deepak Voora, J. Michael Gaziano, Philip S. Tsao, Jessica V. Brewer, Mary T. Brophy, Mary T. Brophy, Lori Churby, Scott L. DuVall, Saiju Pyarajan, Robert Ringer, Luis E. Selva, Shahpoor (Alex) Shayan, Brady Stephens, Stacey B. Whitbourne, Themistocles L. Assimes, Adriana Hung, Henry Kranzler   +43 more
wiley   +1 more source

Breast and Nipple Dermatoses During Lactation

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Lactation and breastfeeding can present both psychological and physical challenges for breastfeeding mothers. In addition, many nursing mothers will also suffer from breast and nipple dermatoses during this period, compounding these difficulties. Common causes of breast and nipple dermatitis during lactation include eczema, psoriasis, mastitis,
Hamish Moore, Annabel Stevenson
wiley   +1 more source

Understanding the Variability of Peanut‐Oral Immunotherapy Responses by Multi‐Omics Profiling of Immune Cells

Allergy, EarlyView.
This study analyzes molecular drivers of OIT responsiveness. Multi‐omics profiling of peanut‐stimulated PBMCs in a controlled peanut‐OIT trial identifies immune, transcriptomic, and epigenetic changes distinguishing complete responders from incomplete responders. Key findings highlight gastrointestinal immune mechanisms, including extracellular exosome
Aleix Arnau‐Soler, Sarah E. Ashley, Ahla Ghauri, Alexander C. S. N. Jeanrenaud, Ingo Marenholz, Katharina Blumchen, Penelope Cibin, Alisa Iakupova, Norbert Hubner, Kirsten Beyer, Young‐Ae Lee   +10 more
wiley   +1 more source

Integration of omics data in the diagnosis and therapy of glioblastoma

Brain Pathology, EarlyView.
Integration of omics data in the diagnosis and therapy of glioblastoma. Abstract Since the 2016 update of the WHO Classification of Tumors of the Central Nervous System, omics data have been officially integrated into the diagnostic process for glioblastoma, the most prevalent and aggressive primary malignant brain tumor in adults.
Constantin Möller, Melanie Schoof, Keith L. Ligon, Ulrich Schüller   +3 more
wiley   +1 more source

Non‐canonical nitric oxide signalling and DNA methylation: Inflammation induced epigenetic alterations and potential drug targets

British Journal of Pharmacology, EarlyView.
Abstract DNA methylation controls DNA accessibility to transcription factors and other regulatory proteins, thereby affecting gene expression and hence cellular identity and function. As epigenetic modifications control the transcriptome, epigenetic dysfunction is strongly associated with pathological conditions and ageing.
Christopher H. Switzer
wiley   +1 more source