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Plant-RRBS, a bisulfite and next-generation sequencing-based methylome profiling method enriching for coverage of cytosine positions [PDF]
BMC Plant Biology, 2017 Background Cytosine methylation in plant genomes is important for the regulation of gene transcription and transposon activity. Genome-wide methylomes are studied upon mutation of the DNA methyltransferases, adaptation to environmental stresses or during
Martin Schmidt +7 more
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Cytosine-to-uracil deamination by SssI DNA methyltransferase. [PDF]
PLoS ONE, 2013 The prokaryotic DNA(cytosine-5)methyltransferase M.SssI shares the specificity of eukaryotic DNA methyltransferases (CG) and is an important model and experimental tool in the study of eukaryotic DNA methylation.
Ildikó Stier, Antal Kiss
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Occurrence, Properties, Applications and Analytics of Cytosine and Its Derivatives [PDF]
MoleculesCytosine and its derivatives are an important research topic in the fields of bioorganic chemistry, molecular biology and medicine due to their key role in the structure and function of nucleic acids.
Mariusz Kluska +3 more
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Frontiers in Immunology, 2022 B-cell acute lymphoblastic leukemia (B-ALL) is the most common childhood malignancy. The cure rate has reached 90% after conventional chemotherapy and hematopoietic stem cell transplantation (HSCT), but the prognosis of patients with relapsed and ...
Lei Deng +10 more
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N-4 Alkyl Cytosine Derivatives Synthesis: A New Approach
Reactions, 2022 The selective N-4 alkylation of cytosine plays a critical role in the synthesis of biologically active molecules. This work focuses on the development of practical reaction conditions toward a regioselective synthesis of N-4-alkyl cytosine derivatives ...
Mauro De Nisco +7 more
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Surface-enhanced Raman spectroscopy of DNA bases [PDF]
, 1986 A Raman microprobe has been used to measure the surface-enhanced Raman spectra of adenine, guanine, cytosine and thymine. Comparison of the SERS spectrum with solution spectra shows that some line positions are not influenced by the adsorption process ...
Greve, J. +3 more
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Molecules, 2021 Thymine DNA Glycosylase (TDG) is an enzyme of the base excision repair mechanism and removes damaged or mispaired bases from DNA via hydrolysis of the glycosidic bond. Specificity is of high importance for such a glycosylase, so as to avoid the damage of
Senta Volkenandt +2 more
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Adsorption of Nucleic Acid Bases, Ribose, and Phosphate by Some Clay Minerals
Life, 2015 Besides having a large capacity for taking up organic molecules, clay minerals can catalyze a variety of organic reactions. Derived from rock weathering, clay minerals would have been abundant in the early Earth. As such, they might be expected to play a
Hideo Hashizume
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Characteristics and efficacy of cytosine and cytidine deaminase [PDF]
مجلة التربية والعلم, 2007 The study concerned with determination of some properties of cytosine deaminase activity in serum and erythrocytes haemolysate in normal human individuals, by spectral method.
Qusay Chalabi, Zahraa Hammodat
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Frontiers in Chemistry, 2018 Cytosine, a DNA and RNA building-block, and Metformin, the most widely prescribed drug for the treatment of Type 2 Diabetes mellitus were made to react separately with ammonium or sodium metavanadates in acidic aqueous solutions to obtain two ...
Eduardo Sánchez-Lara +7 more
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