Results 31 to 40 of about 233,386 (297)
Cytosine Methylation: Remaining Faithful [PDF]
DNA methyltransferase-1 (DNMT1) has a higher specific activity on hemimethylated DNA than on unmethylated DNA, but this preference is too small to explain the faithful mitotic inheritance of genomic methylation patterns. New genetic studies in plants and mammals have identified a novel factor that increases the fidelity of maintenance methylation.
Ooi, Steen K.T., Bestor, Timothy H.
openaire +2 more sources
Background Literature reports that mature microRNA (miRNA) can be methylated at adenosine, guanosine and cytosine. However, the molecular mechanisms involved in cytosine methylation of miRNAs have not yet been fully elucidated.
Mathilde Cheray +15 more
doaj +1 more source
Ureido cytosine and cytosine-containing acrylic copolymers
Ureido-cytosine pendant groups contributed to random acrylic copolymers with enhanced thermomechanical performance, well-defined morphologies, and reduced water uptake.
Keren Zhang +6 more
openaire +2 more sources
Consecutive Silver(I) Ion Incorporation into Oligonucleotides containing Cytosine‐Cytosine Mispairs [PDF]
AbstractInvited for this month's cover is the group of Prof. Heinz‐Bernhard Kraatz from the University of Toronto, Canada. The cover picture shows the consecutive incorporation of AgI ions into a DNA duplex containing adjacent C−C mispairs. Read the full text of the article at 10.1002/cplu.202000607.
M. Nur Hossain +2 more
openaire +3 more sources
Enzymatic approaches for profiling cytosine methylation and hydroxymethylation
Background: In mammals, modifications to cytosine bases, particularly in cytosine-guanine (CpG) dinucleotide contexts, play a major role in shaping the epigenome.
Tong Wang +2 more
doaj +1 more source
Dual-tip-enhanced ultrafast CARS nanoscopy [PDF]
Coherent anti-Stokes Raman scattering (CARS) and, in particular, femtosecond adaptive spectroscopic techniques (FAST CARS) have been successfully used for molecular spectroscopy and microscopic imaging.
+15 more
core +3 more sources
Non-Empirically Tuned Range-Separated DFT Accurately Predicts Both Fundamental and Excitation Gaps in DNA and RNA Nucleobases [PDF]
Using a non-empirically tuned range-separated DFT approach, we study both the quasiparticle properties (HOMO-LUMO fundamental gaps) and excitation energies of DNA and RNA nucleobases (adenine, thymine, cytosine, guanine, and uracil).
Foster, Michael E., Wong, Bryan M.
core +2 more sources
A mutant of uracil DNA glycosylase that distinguishes between cytosine and 5-methylcytosine. [PDF]
We demonstrate that a mutant of uracil DNA glycosylase (N123D:L191A) distinguishes between cytosine and methylcytosine. Uracil DNA glycosylase (UDG) efficiently removes uracil from DNA in a reaction in which the base is flipped into the enzyme's active ...
Scott T Kimber, Tom Brown, Keith R Fox
doaj +1 more source
Factors Influencing the Nitrogen-Source Dependent Flucytosine Resistance in Cryptococcus Species
Flucytosine (5-FC) is an antifungal agent commonly used for treatment of cryptococcosis and several other systemic mycoses. In fungi, cytosine permease and cytosine deaminase are known major players in flucytosine resistance by regulating uptake and ...
Dong-Hoon Yang +3 more
doaj +1 more source
A TDDFT study of the excited states of DNA bases and their assemblies [PDF]
We present a detailed study of the optical absorption spectra of DNA bases and base pairs, carried out by means of time dependent density functional theory.
Di Felice, R. +3 more
core +2 more sources

