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Biogenic Guanine Crystals Are Solid Solutions of Guanine and Other Purine Metabolites [PDF]

open access: yesJournal of the American Chemical Society, 2022
Highly reflective crystals of the nucleotide base guanine are widely distributed in animal coloration and visual systems. Organisms precisely control the morphology and organization of the crystals to optimize different optical effects, but little is known about how this is achieved.
Avital Wagner   +2 more
exaly   +4 more sources

Guanine-vacancy–bearing G-quadruplexes responsive to guanine derivatives [PDF]

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2015
Significance Guanine-rich nucleic acids fold into a four-stranded structure named G-quadruplex that has implications in essential cellular processes, pharmaceutical applications, and nanodevices. We found a unique type of G-quadruplex that contains a G-vacancy and is stabilized by guanine derivatives such as te physiological concentration of ...
Ke-Wei Zheng   +2 more
exaly   +3 more sources

Underlying charge-transfer mechanism of visible light emission in guanine crystals [PDF]

open access: yesCommunications Chemistry
Biogenic guanine crystals found in various aquatic and terrestrial animals, show unique optical properties that include structural coloration as well as reflectance and have intrigued researchers for over a century.
Aditya Prasun   +5 more
doaj   +2 more sources

Detection of Pathogens and Antimicrobial Resistance Genes at Low Concentration via Electrochemical Oligonucleotide Tags

open access: yesEngineering Proceedings, 2023
Pathogens can be detected electrochemically by measuring guanine oxidation signals generated from RNA or DNA hybridized to a biosensor working electrode. However, the associated limit of detection (LOD) is not sufficiently low for widespread clinical use.
Neil Gordon, Raj Bawa, Garry Palmateer
doaj   +1 more source

Fluorescence Assay for Detecting Four Organophosphorus Pesticides Using Fluorescently Labeled Aptamer

open access: yesSensors, 2022
In this work, we reported a rapid and sensitive fluorescence assay in homogenous solution for detecting organophosphorus pesticides by using tetramethylrhodamine (TAMRA)-labeled aptamer and its complementary DNA (cDNA) with extended guanine (G) bases ...
He Li   +6 more
doaj   +1 more source

Au Nanoparticles on 4-Thiophenol-Electrodeposited Carbon Surfaces for the Simultaneous Detection of 8-Hydroxyguanine and Guanine

open access: yesChemosensors, 2023
In this proof-of-concept study, gold nanoparticles (AuNPs) were immobilized on glassy carbon electrode (GCE) surfaces using a surface-anchored diazonium salt of 4-aminothiophenol (GCE-Ph-S-AuNPs).
Niloufar Soltani   +3 more
doaj   +1 more source

Molecular Self-Assembly of an Unusual Dinuclear Ruthenium(III) Complex Based on the Nucleobase Guanine

open access: yesCrystals, 2022
The study of crystal structures based on complexes containing purine nucleobases is a significant research subject, mainly regarding the diagnosis and treatment of some diseases and the investigation of genetic mutations and biochemical structures in ...
Marta Orts-Arroyo   +3 more
doaj   +1 more source

Theoretical Assessment of the Ligand/Metal/Quadruplex Recognition in the Non-Canonical Nucleic Acids Structures

open access: yesMolecules, 2023
Quadruplexes (GQs), peculiar DNA/RNA motifs concentrated in specific genomic regions, play a vital role in biological processes including telomere stability and, hence, represent promising targets for anticancer therapy. GQs are formed by folding guanine-
Nikoleta Kircheva   +5 more
doaj   +1 more source

Infrared Spectral Signatures of Nucleobases in Interstellar Ices I: Purines

open access: yesLife, 2023
The purine nucleobases adenine and guanine are complex organic molecules that are essential for life. Despite their ubiquitous presence on Earth, purines have yet to be detected in observations of astronomical environments.
Caroline Antunes Rosa   +11 more
doaj   +1 more source

Diversity of Parallel Guanine Quadruplexes Induced by Guanine Substitutions [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Recently, we reported an inhibitory effect of guanine substitutions on the conformational switch from antiparallel to parallel quadruplexes (G4) induced by dehydrating agents. As a possible cause, we proposed a difference in the sensitivity of parallel and antiparallel quadruplexes to the guanine substitutions in the resulting thermodynamic stability ...
Klára Bednářová   +2 more
openaire   +2 more sources

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