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Biogenic Guanine Crystals Are Solid Solutions of Guanine and Other Purine Metabolites
Journal of the American Chemical Society, 2022 Highly reflective crystals of the nucleotide base guanine are widely distributed in animal coloration and visual systems. Organisms precisely control the morphology and organization of the crystals to optimize different optical effects, but little is ...
Noam Pinsk, Avital Wagner, Lilian Cohen
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Guanine-vacancy–bearing G-quadruplexes responsive to guanine derivatives [PDF]
Proceedings of the National Academy of Sciences, 2015 Significance Guanine-rich nucleic acids fold into a four-stranded structure named G-quadruplex that has implications in essential cellular processes, pharmaceutical applications, and nanodevices. We found a unique type of G-quadruplex that contains a G-vacancy and is stabilized by guanine derivatives such as te physiological concentration of ...
Xin-min, Li +7 more
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Generation, repair and replication of guanine oxidation products
Genes and Environment, 2017 Guanine is the most readily oxidized of the four DNA bases, and guanine oxidation products cause G:C-T:A and G:C-C:G transversions through DNA replication.
Katsuhito Kino +4 more
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Underlying charge-transfer mechanism of visible light emission in guanine crystals [PDF]
Communications ChemistryBiogenic guanine crystals found in various aquatic and terrestrial animals, show unique optical properties that include structural coloration as well as reflectance and have intrigued researchers for over a century.
Aditya Prasun +5 more
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Applications of guanine quartets in nanotechnology and chemical biology
Nature Reviews Chemistry, 2019 Loic Stefan, David Monchaud
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Engineering Proceedings, 2023 Pathogens can be detected electrochemically by measuring guanine oxidation signals generated from RNA or DNA hybridized to a biosensor working electrode. However, the associated limit of detection (LOD) is not sufficiently low for widespread clinical use.
Neil Gordon, Raj Bawa, Garry Palmateer
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Crystals, 2021 The aim of the work was to synthesize new perspective compounds of palladium and platinum with nitrogenous bases (guanine), promising for use in biomedicine and catalysis. The article describes the synthesis of new [PdCl2(HGua)2]Cl2·H2O and [PtCl5(HGua)]·
Anton Petrovich Novikov +4 more
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Frontiers in Pharmacology, 2021 Neuroblastoma arises from neural crest cell precursors failing to complete the process of differentiation. Thus, agents helping tumor cells to differentiate into normal cells can represent a valid therapeutic strategy.
Natale Belluardo +13 more
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Oxidation of the Guanine Nucleotide Pool Underlies Cell Death by Bactericidal Antibiotics
Science, 2012 James J Collins, Graham C Walker
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Diversity of Parallel Guanine Quadruplexes Induced by Guanine Substitutions [PDF]
International Journal of Molecular Sciences, 2020 Recently, we reported an inhibitory effect of guanine substitutions on the conformational switch from antiparallel to parallel quadruplexes (G4) induced by dehydrating agents. As a possible cause, we proposed a difference in the sensitivity of parallel and antiparallel quadruplexes to the guanine substitutions in the resulting thermodynamic stability ...
Klára Bednářová +2 more
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