Results 41 to 50 of about 3,741 (114)

Synergistic Regulation of Pigment Cell Precursors’ Differentiation and Migration by ednrb1a and ednrb2 in Nile Tilapia

open access: yesCells
The evolutionary loss of ednrb2 in specific vertebrate lineages, such as mammals and cypriniform fish, raises fundamental questions about its functional necessity and potential redundancy or synergy with paralogous endothelin receptors in pigment cell ...
Zilong Wen   +7 more
doaj   +1 more source

Radiological Evaluation of Huntington’s Disease: A Case Report [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Huntington’s Disease (HD) is a rare neurodegenerative condition inherited in an autosomal dominant pattern, where Gamma Amino Butyric Acid-ergic (GABAergic) neurons in the basal ganglia progressively deteriorate.
Soumyabrata Debnath, R Harshith
doaj   +1 more source

The intermolecular dimer potential for guanine

open access: yesThe Journal of Chemical Physics, 2017
The ab initio intermolecular potential of guanine has been developed with the help of a combination of symmetry-adapted perturbation theory and density functional theory (DFT). The resulting potential has been globally optimized to locate the guanine cluster structures up to tetramers.
Artür Manukyan, Adem Tekin
openaire   +3 more sources

Direct determination of guanine in Aciclovir Dispersible Tablets solution by acylpyrazolone modified glassy carbon electrode

open access: yesReviews in Analytical Chemistry, 2011
In this article, the investigation of electrochemical determination of guanine(GU) by 1-phenyl-3-methyl-4-(2-furoyl)-5-pyrazolone (HPMαFP) modified glassy carbon electrode (HPMαFP/GCE) in Aciclovir Dispersible Tablets solution was reported.
Li Xueli, Li Jinzhou
doaj   +1 more source

An Electrochemical DNA Biosensor for Carcinogenicity of Anticancer Compounds Based on Competition between Methylene Blue and Oligonucleotides

open access: yesSensors, 2019
A toxicity electrochemical DNA biosensor has been constructed for the detection of carcinogens using 24 base guanine DNA rich single stranded DNA, and methylene blue (MB) as the electroactive indicator.
Nor Diyana Md. Sani   +7 more
doaj   +1 more source

Synthetic Routes to N-9 Alkylated 8-Oxoguanines; Weak Inhibitors of the Human DNA Glycosylase OGG1

open access: yesMolecules, 2015
The human 8-oxoguanine DNA glycosylase OGG1 is involved in base excision repair (BER), one of several DNA repair mechanisms that may counteract the effects of chemo- and radiation therapy for the treatment of cancer. We envisage that potent inhibitors of
Tushar R. Mahajan   +4 more
doaj   +1 more source

Guanine Deaminase Stimulates Ultraviolet-induced Keratinocyte Senescence in Seborrhoeic Keratosis via Guanine Metabolites

open access: yesActa Dermato-Venereologica, 2020
DNA damage and oxidative stress play a critical role in photoageing. Seborrhoeic keratosis (SK) affects sunlight-exposed sites in aged individuals. This study examined the mechanism of photoageing in SK.
Kyung Ah Cheong, Ai-Young Lee
doaj   +1 more source

Crystal structure of disodium 2-amino-6-oxo-6,7-dihydro-1H-purine-1,7-diide heptahydrate

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, disodium 2-amino-6-oxo-6,7-dihydro-1H-purine-1,7-diide heptahydrate, 2Na+·C5H3N5O2−·7H2O, the structure is composed of alternating (100) layers of guanine molecules and hydrated Na+ ions. Within the guanine layer, the molecules are
Dvir Gur, Linda J. W. Shimon
doaj   +1 more source

Partial Replacement of Fish Meal with Fish Scale Meal Enhances Body Color Brightness and Iridophore Development in Koi (Cyprinus carpio var. koi)

open access: yesAnimals
Body color brightness is a key determinant of ornamental value in koi, yet nutritional strategies targeting structural coloration mediated by iridophores remain underexplored.
Shengyu Gao   +9 more
doaj   +1 more source

Intermediate filaments spatially organize intracellular nanostructures to produce the bright structural blue of ribbontail stingrays across ontogeny

open access: yesFrontiers in Cell and Developmental Biology
In animals, pigments but also nanostructures determine skin coloration, and many shades are produced by combining both mechanisms. Recently, we discovered a new mechanism for blue coloration in the ribbontail stingray Taeniura lymma, a species with ...
Michael J. Blumer   +7 more
doaj   +1 more source

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