Results 41 to 50 of about 369,753 (339)

Crystal structure of the nucleoside 2′-deoxyguanosine dimethyl sulfoxide disolvate

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2023
The title compound, C10H13N5O4·2C2H6OS, which is of interest with respect to its biological activity, at 183 K has orthorhombic (P212121) crystal symmetry. The structure displays a network of intermolecular N—H...N, N—H...O and O—H...O hydrogen bonds. 2′-
Bernhard Spingler
doaj   +1 more source

A new possible way for cancer cure – DNA four strand [PDF]

open access: yesWorld Cancer Research Journal, 2019
DNA is the active ingredient of all the biological operations of the cell because it stores genetic information in the configuration of genes. It is a very well recognized fact that DNA has a double-helical structure; recently, it was reported to have ...
P. Amit, K. Prerna, S. Anita, S. Kumar
doaj   +1 more source

Products of Oxidative Guanine Damage Form Base Pairs with Guanine [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Among the natural bases, guanine is the most oxidizable base. The damage caused by oxidation of guanine, commonly referred to as oxidative guanine damage, results in the formation of several products, including 2,5-diamino-4H-imidazol-4-one (Iz), 2,2,4-triamino-5(2H)-oxazolone (Oz), guanidinoformimine (Gf), guanidinohydantoin/iminoallantoin (Gh/Ia ...
Katsuhito Kino   +4 more
openaire   +2 more sources

An organometallic compound which exhibits a DNA topology-dependent one-stranded intercalation mode [PDF]

open access: yes, 2016
Understanding how small molecules interact with DNA is essential since it underlies a multitude of pathological conditions and therapeutic interventions.
Adhireksan   +16 more
core   +3 more sources

The Origin of Life: Models and Data. [PDF]

open access: yes, 2017
A general framework for conventional models of the origin of life (OOL) is the specification of a 'privileged function.' A privileged function is an extant biological function that is excised from its biological context, elevated in importance over other
Lanier, Kathryn A, Williams, Loren Dean
core   +1 more source

Surface-Enhanced Hyper-Raman Spectra of Adenine, Guanine, Cytosine, Thymine, and Uracil

open access: yesThe journal of physical chemistry. C, Nanomaterials and interfaces, 2016
Using picosecond excitation at 1064 nm, surface-enhanced hyper-Raman scattering (SEHRS) spectra of the nucleobases adenine, guanine, cytosine, thymine, and uracil with two different types of silver nanoparticles were obtained. Comparing the SEHRS spectra
F. Madzharova   +3 more
semanticscholar   +1 more source

Base composition of DNA in adenovirus-12-induced tumor [PDF]

open access: yes, 1969
A series of experiments was conducted to study the base composition of DNA in AVl2-induced tumor and host cells by paper chromatography, and it was found that DNA per cent. guanine-cystosine contents were around 42 % in both of them. The base composition
Ohmori, Masaki
core   +1 more source

Platinum Compound on Gold–Magnesia Hybrid Structure: A Theoretical Investigation on Adsorption, Hydrolysis, and Interaction with DNA Purine Bases

open access: yesNanomaterials
Cisplatin-based platinum compounds are important clinical chemotherapeutic agents that participate in most tumor chemotherapy regimens. Through density-functional theory calculations, the formation and stability of the inorganic oxide carrier, the ...
Zhenjun Song   +6 more
doaj   +1 more source

Radiological Evaluation of Huntington’s Disease: A Case Report [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Huntington’s Disease (HD) is a rare neurodegenerative condition inherited in an autosomal dominant pattern, where Gamma Amino Butyric Acid-ergic (GABAergic) neurons in the basal ganglia progressively deteriorate.
Soumyabrata Debnath, R Harshith
doaj   +1 more source

A guanine-flipping and sequestration mechanism for G-quadruplex unwinding by RecQ helicases

open access: yesNature Communications, 2018
Homeostatic regulation of G-quadruplexes (G4s), four-stranded structures that can form in guanine-rich nucleic acids, requires G4 unwinding helicases. The mechanisms that mediate G4 unwinding remain unknown.
A. F. Voter   +4 more
semanticscholar   +1 more source

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