Results 21 to 30 of about 3,741 (114)

Products of Oxidative Guanine Damage Form Base Pairs with Guanine [PDF]

International Journal of Molecular Sciences, 2020
Among the natural bases, guanine is the most oxidizable base. The damage caused by oxidation of guanine, commonly referred to as oxidative guanine damage, results in the formation of several products, including 2,5-diamino-4H-imidazol-4-one (Iz), 2,2,4-triamino-5(2H)-oxazolone (Oz), guanidinoformimine (Gf), guanidinohydantoin/iminoallantoin (Gh/Ia ...
Katsuhito Kino, Taishu Kawada, Masayo Hirao-Suzuki, Masayuki Morikawa, Hiroshi Miyazawa   +4 more
openaire   +2 more sources

Au Nanoparticles on 4-Thiophenol-Electrodeposited Carbon Surfaces for the Simultaneous Detection of 8-Hydroxyguanine and Guanine

Chemosensors, 2023
In this proof-of-concept study, gold nanoparticles (AuNPs) were immobilized on glassy carbon electrode (GCE) surfaces using a surface-anchored diazonium salt of 4-aminothiophenol (GCE-Ph-S-AuNPs).
Niloufar Soltani, Qusai Hassan, Meissam Noroozifar, Kagan Kerman   +3 more
doaj   +1 more source

Detection of Guanine and Adenine Using an Aminated Reduced Graphene Oxide Functional Membrane-Modified Glassy Carbon Electrode

Sensors, 2017
A new electrochemical sensor based on a Nafion, aminated reduced graphene oxide and chitosan functional membrane-modified glassy carbon electrode was proposed for the simultaneous detection of adenine and guanine. Fourier transform-infrared spectrometry (
Di Li, Xiao-Lu Yang, Bao-Lin Xiao, Fang-Yong Geng, Jun Hong, Nader Sheibani, Ali Akbar Moosavi-Movahedi   +6 more
doaj   +1 more source

Molecular Self-Assembly of an Unusual Dinuclear Ruthenium(III) Complex Based on the Nucleobase Guanine

Crystals, 2022
The study of crystal structures based on complexes containing purine nucleobases is a significant research subject, mainly regarding the diagnosis and treatment of some diseases and the investigation of genetic mutations and biochemical structures in ...
Marta Orts-Arroyo, Adriana Silvestre-Llora, Isabel Castro, José Martínez-Lillo   +3 more
doaj   +1 more source

Electrochemical antioxidant screening and evaluation based on guanine and chitosan immobilized MoS2 nanosheet modified glassy carbon electrode (guanine/CS/MoS2/GCE)

Open Chemistry, 2020
In this study, an electrochemical biosensor based on guanine and chitosan immobilized MoS2 nanosheet modified glassy carbon electrode (guanine/CS/MoS2/GCE) was developed and employed for antioxidant screening and antioxidant capacity evaluation.
Tang Ping, Tang Xiaosheng, Mei Shiyong, Xie Yixi, Liu Liangliang, Ren Licheng   +5 more
doaj   +1 more source

Modulation of guanine deaminase [PDF]

Biochemical Journal, 1973
1. Guanine deaminases purified from the 15000g supernatant fraction of iso-osmotic sucrose homogenates of rat and mouse liver and brain were tested for the influence of GTP and allantoin. 2. The suffixes A and B were assigned to the isoenzyme fractions eluted from DEAE-cellulose with the lower and the higher molarity of eluent respectively. Isoenzyme A
K S, Kumar, A, Sitaramayya, P S, Krishnan   +2 more
openaire   +2 more sources

Electrochemical and theoretical evaluation of the interaction between dna and amodiaquine: evidence of the guanine adduct formation

Química Nova, 2010
The electrochemical behavior of the interaction of amodiaquine with DNA on a carbon paste electrode was studied using voltametric techniques. In an acid medium, an electroactive adduct is formed when amodiaquine interacts with DNA.
Maria Lara P. M. Arguelho, José do Patrocínio H. Alves, Nelson R. Stradiotto, Valdemar Lacerda Júnior, José Maria Pires, Adilson Beatriz   +5 more
doaj   +1 more source

Theoretical Assessment of the Ligand/Metal/Quadruplex Recognition in the Non-Canonical Nucleic Acids Structures

Molecules, 2023
Quadruplexes (GQs), peculiar DNA/RNA motifs concentrated in specific genomic regions, play a vital role in biological processes including telomere stability and, hence, represent promising targets for anticancer therapy. GQs are formed by folding guanine-
Nikoleta Kircheva, Stefan Dobrev, Vladislava Petkova, Snezhana Bakalova, Jose Kaneti, Silvia Angelova   +5 more
doaj   +1 more source

Simultaneous Determination of Four DNA bases at Graphene Oxide/Multi-Walled Carbon Nanotube Nanocomposite-Modified Electrode

Micromachines, 2020
In this study, we developed a modified glassy carbon electrode (GCE) with graphene oxide, multi-walled carbon nanotube hybrid nanocomposite in chitosan (GCE/GO-MWCNT-CHT) to achieve simultaneous detection of four nucleobases (i.e., guanine (G), adenine ...
Shuting Wang, Celia Ferrag, Meissam Noroozifar, Kagan Kerman   +3 more
doaj   +1 more source

Infrared Spectral Signatures of Nucleobases in Interstellar Ices I: Purines

Life, 2023
The purine nucleobases adenine and guanine are complex organic molecules that are essential for life. Despite their ubiquitous presence on Earth, purines have yet to be detected in observations of astronomical environments.
Caroline Antunes Rosa, Alexandre Bergantini, Péter Herczku, Duncan V. Mifsud, Gergő Lakatos, Sándor T. S. Kovács, Béla Sulik, Zoltán Juhász, Sergio Ioppolo, Heidy M. Quitián-Lara, Nigel J. Mason, Claudia Lage   +11 more
doaj   +1 more source