Results 21 to 30 of about 369,753 (339)

Eco-Friendly Synthesis of Nitrogen-Doped Mesoporous Carbon for Supercapacitor Application

open access: yesC, 2018
A sustainable and simple synthesis procedure involving the co-assembly of green phenolic resin and amphiphilic polymer template in water/ethanol mixture at room temperature to synthesize nitrogen doped mesoporous carbon is reported herein.
Georges Moussa   +4 more
doaj   +1 more source

Concurrent use of rabacfosadine and L‐asparaginase for relapsed or refractory multicentric lymphoma in dogs

open access: yesJournal of Veterinary Internal Medicine, 2020
Background Rabacfosadine (RAB), a novel antineoplastic agent conditionally licensed for the treatment of lymphoma in dogs, is efficacious in both naïve and previously treated dogs.
Jacob R. Cawley   +8 more
doaj   +1 more source

Nickel(II)-catalysed oxidative guanine and DNA damage beyond 8-oxoguanine [PDF]

open access: yes, 2007
Oxidative DNA damage is one of the most important and most studied mechanisms of disease. It has been associated with a range of terminal diseases such as cancer, heart disease, hepatitis, and HIV, as well as with a variety of everyday ailments.
Kelly, Michele C.   +3 more
core   +1 more source

Uncovering the Signaling Pathway behind Extracellular Guanine-Induced Activation of NO System: New Perspectives in Memory-Related Disorders

open access: yesFrontiers in Pharmacology, 2018
Mounting evidence suggests that the guanine-based purines stand out as key player in cell metabolism and in several models of neurodegenerative disorders, such as Parkinson’s and Alzheimer’s diseases.
Mariachiara Zuccarini   +18 more
doaj   +1 more source

Long-term Nucleotide Analogue Treatment Has Higher Levels of Renal Toxicities than Does Entecavir in Patients with Chronic Hepatitis B

open access: yesGut and Liver, 2020
Background/Aims: Renal toxicity is a concern in patients with chronic hepatitis B taking nucleotide analogues, such as adefovir (ADV) and tenofovir disoproxil fumarate (TDF).
Young Youn Cho   +8 more
doaj   +1 more source

Structure and singly occupied molecular orbital analysis of anionic tautomers of guanine [PDF]

open access: yes, 2008
Recently we reported the discovery of adiabatically bound anions of guanine which might be involved in the processes of DNA damage by low-energy electrons and in charge transfer through DNA.
Abdoul-Carime   +42 more
core   +1 more source

Oxidative Stress: Role and Response of Short Guanine Tracts at Genomic Locations

open access: yesInternational Journal of Molecular Sciences, 2019
Over the decades, oxidative stress has emerged as a major concern to biological researchers. It is involved in the pathogenesis of various lifestyle-related diseases such as hypertension, diabetes, atherosclerosis, and neurodegenerative diseases.
Anju Singh   +3 more
semanticscholar   +1 more source

Interplay of 'induced fit' and preorganization in the ligand induced folding of the aptamer domain of the guanine binding riboswitch [PDF]

open access: yes, 2006
Riboswitches are highly structured elements in the 50-untranslated regions (50-UTRs) of messenger RNA that control gene expression by specifically binding to small metabolite molecules. They consist of an aptamer domain responsible for ligand binding and
Noeske, Jonas   +5 more
core   +1 more source

The Two Faces of the Guanyl Radical: Molecular Context and Behavior

open access: yesMolecules, 2021
The guanyl radical or neutral guanine radical G(-H)• results from the loss of a hydrogen atom (H•) or an electron/proton (e–/H+) couple from the guanine structures (G). The guanyl radical exists in two tautomeric forms.
Chryssostomos Chatgilialoglu
doaj   +1 more source

Tautomerism of Guanine Analogues [PDF]

open access: yesBiomolecules, 2020
Tautomerism of nucleic acid (NA) bases is a crucial factor for the maintenance and translation of genetic information in organisms. Only canonical tautomers of NA bases can form hydrogen-bonded complexes with their natural counterparts. On the other hand, rare tautomers of nucleobases have been proposed to be involved in processes catalysed by NA ...
Jakub Radek Štoček   +1 more
openaire   +3 more sources

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