Results 21 to 30 of about 191,107 (300)

Modulation of guanine deaminase [PDF]

Biochemical Journal, 1973
1. Guanine deaminases purified from the 15000g supernatant fraction of iso-osmotic sucrose homogenates of rat and mouse liver and brain were tested for the influence of GTP and allantoin. 2. The suffixes A and B were assigned to the isoenzyme fractions eluted from DEAE-cellulose with the lower and the higher molarity of eluent respectively. Isoenzyme A
K S, Kumar, A, Sitaramayya, P S, Krishnan   +2 more
openaire   +2 more sources

Gas-Phase Studies of Hypoxanthine-Guanine-(Xanthine) Phosphoribosyltransferase (HG(X)PRT) Substrates

, 2023
The gas-phase acidity and proton affinity of nucleobases that are substrates for the enzyme Plasmodium falciparum hypoxanthine-guanine-(xanthine) phosphoribosyltransferase (Pf HG(X)PRT) have been examined using both computational and experimental methods.
Lanxin Zhang, Lanxin Zhang (11874204), G. S. M. Kiruba (2709949), Jeehiun K. Lee, Jeehiun K. Lee (1575025), G. S. M. Kiruba   +5 more
core   +1 more source

Protonated nucleobases are not fully ionized in their chloride salt crystals and form metastable base pairs further stabilized by the surrounding anions

IUCrJ, 2018
This paper presents experimental charge-density studies of cytosinium chloride, adeninium chloride hemihydrate and guaninium dichloride crystals based on ultra-high-resolution X-ray diffraction data and extensive theoretical calculations.
Prashant Kumar, Malgorzata Katarzyna Cabaj, Aleksandra Pazio, Paulina Maria Dominiak   +3 more
doaj   +1 more source

Synthesis and Characterization of New Guanine Complexes of Pt(IV) and Pd(II) by X-ray Diffraction and Hirshfeld Surface Analysis

Crystals, 2021
The aim of the work was to synthesize new perspective compounds of palladium and platinum with nitrogenous bases (guanine), promising for use in biomedicine and catalysis. The article describes the synthesis of new [PdCl2(HGua)2]Cl2·H2O and [PtCl5(HGua)]·
Anton Petrovich Novikov, Mikhail Alexandrovich Volkov, Alexey Vladimirovich Safonov, Mikhail Semenovich Grigoriev, Evgeny Vladilenovich Abkhalimov   +4 more
doaj   +1 more source

Investigating the Role of Guanosine on Human Neuroblastoma Cell Differentiation and the Underlying Molecular Mechanisms

Frontiers in Pharmacology, 2021
Neuroblastoma arises from neural crest cell precursors failing to complete the process of differentiation. Thus, agents helping tumor cells to differentiate into normal cells can represent a valid therapeutic strategy.
Natale Belluardo, Giuseppa Mudò, Valentina Di Liberto, Monica Frinchi, Daniele F. Condorelli, Ugo Traversa, Francisco Ciruela, Francisco Ciruela, Renata Ciccarelli, Renata Ciccarelli, Patrizia Di Iorio, Patrizia Di Iorio, Patricia Giuliani, Patricia Giuliani   +13 more
doaj   +1 more source

Guanine quantum defects in carbon nanotubes for biosensing

, 2023
Fluorescent single wall carbon nanotubes (SWCNTs) are used as nanoscale biosensors in diverse applications. Selectivity is built in by non-covalent functionalization with polymers such as DNA.
Phillip, Galonska, Lena, Schnitzler, C. Alexander, Schrage, Jennifer M., Mohr, Sebastian, Kruss   +4 more
core   +1 more source

Cytogenetic changes in irradiated rats under influence of guaninium-zinc chloride complex

Фактори експериментальної еволюції організмів, 2023
Aim. The main goal of this study was to study the anti-radiation effect of guaninium-zinc chloride complex on cytogenetic changes in irradiated rats. Methods.
E. N. Shamilov, A. S. Abdullayev, V. E. Shamilli, M. F. Farajov, I. V. Azizov, K. A. Hajiyev, A. A. Jalilova   +6 more
doaj   +1 more source

Radiological Evaluation of Huntington’s Disease: A Case Report [PDF]

Journal of Clinical and Diagnostic Research
Huntington’s Disease (HD) is a rare neurodegenerative condition inherited in an autosomal dominant pattern, where Gamma Amino Butyric Acid-ergic (GABAergic) neurons in the basal ganglia progressively deteriorate.
Soumyabrata Debnath, R Harshith
doaj   +1 more source

The Two Faces of the Guanyl Radical: Molecular Context and Behavior

Molecules, 2021
The guanyl radical or neutral guanine radical G(-H)• results from the loss of a hydrogen atom (H•) or an electron/proton (e–/H+) couple from the guanine structures (G). The guanyl radical exists in two tautomeric forms.
Chryssostomos Chatgilialoglu
doaj   +1 more source

NupR Responding to Multiple Signals Is a Nucleoside Permease Regulator in Bacillus thuringiensis BMB171

Microbiology Spectrum, 2022
Nucleoside transport is essential for maintaining intracellular nucleoside and nucleobase homeostasis for living cells. Here, we identified an uncharacterized GntR/HutC family transcriptional regulator, NagR2, renamed NupR (nucleoside permease regulator),
Jiaxin Qin, Zhanglei Cao, Xia Cai, Yu Fang, Baoju An, Xuelian Li, Yizhuo Zhang, Hongwei Tian, Wenzhuo Hu, Bing Yan, Jun Cai   +10 more
doaj   +1 more source