Results 11 to 20 of about 38,557 (248)

Investigating the Role of Guanosine on Human Neuroblastoma Cell Differentiation and the Underlying Molecular Mechanisms

Frontiers in Pharmacology, 2021
Neuroblastoma arises from neural crest cell precursors failing to complete the process of differentiation. Thus, agents helping tumor cells to differentiate into normal cells can represent a valid therapeutic strategy.
Natale Belluardo, Giuseppa Mudò, Valentina Di Liberto, Monica Frinchi, Daniele F. Condorelli, Ugo Traversa, Francisco Ciruela, Francisco Ciruela, Renata Ciccarelli, Renata Ciccarelli, Patrizia Di Iorio, Patrizia Di Iorio, Patricia Giuliani, Patricia Giuliani   +13 more
doaj   +1 more source

BiAPoL/guanine-crystal-analysis: 0.0.2

, 2023
What's Changed Execution from folder by @marabuuu in https://github.com/BiAPoL/guanine-crystal-analysis/pull/2 Documentation by @marabuuu in https://github.com/BiAPoL/guanine-crystal-analysis/pull/5 Execution from folder by @marabuuu in https://github ...
Mara Lampert, Robert Haase
core   +1 more source

Selective Functionalization at N2-Position of Guanine in Oligonucleotides via Reductive Amination [PDF]

, 2020
Chemo- and site-specific modifications in oligonucleotides have wide applicability as mechanistic probes in chemical biology. Here we have employed a classical reaction in organic chemistry, reductive amination, to selectively functionalize the N2-amine ...
Bapurao, Bhoge, Ishu, Saraogi
core   +1 more source

Cytogenetic changes in irradiated rats under influence of guaninium-zinc chloride complex

Фактори експериментальної еволюції організмів, 2023
Aim. The main goal of this study was to study the anti-radiation effect of guaninium-zinc chloride complex on cytogenetic changes in irradiated rats. Methods.
E. N. Shamilov, A. S. Abdullayev, V. E. Shamilli, M. F. Farajov, I. V. Azizov, K. A. Hajiyev, A. A. Jalilova   +6 more
doaj   +1 more source

Guanine-Specific Chemical Reaction Reveals ssDNA Interactions on Carbon Nanotube Surfaces

, 2022
Understanding the conformations of physisorbed single-stranded DNA (ssDNA) oligos on single-wall carbon nanotube (SWCNT) surfaces is important for advancing basic nanoscience and for developing applications in biomedicine and quantum information ...
Ali A. Alizadehmojarad, Yu Zheng (2950), Sergei M. Bachilo (1366209), Ali A. Alizadehmojarad (5895983), R. Bruce Weisman (1366206), R. Bruce Weisman, Yu Zheng, Sergei M. Bachilo   +7 more
core   +1 more source

Fluorescence Assay for Detecting Four Organophosphorus Pesticides Using Fluorescently Labeled Aptamer

Sensors, 2022
In this work, we reported a rapid and sensitive fluorescence assay in homogenous solution for detecting organophosphorus pesticides by using tetramethylrhodamine (TAMRA)-labeled aptamer and its complementary DNA (cDNA) with extended guanine (G) bases ...
He Li, Xue Huang, Jingcheng Huang, Mengyuan Bai, Mengjiao Hu, Yemin Guo, Xia Sun   +6 more
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Au Nanoparticles on 4-Thiophenol-Electrodeposited Carbon Surfaces for the Simultaneous Detection of 8-Hydroxyguanine and Guanine

Chemosensors, 2023
In this proof-of-concept study, gold nanoparticles (AuNPs) were immobilized on glassy carbon electrode (GCE) surfaces using a surface-anchored diazonium salt of 4-aminothiophenol (GCE-Ph-S-AuNPs).
Niloufar Soltani, Qusai Hassan, Meissam Noroozifar, Kagan Kerman   +3 more
doaj   +1 more source

Interplay of 'induced fit' and preorganization in the ligand induced folding of the aptamer domain of the guanine binding riboswitch [PDF]

, 2006
Riboswitches are highly structured elements in the 50-untranslated regions (50-UTRs) of messenger RNA that control gene expression by specifically binding to small metabolite molecules. They consist of an aptamer domain responsible for ligand binding and
Wöhnert, Jens, Nasiri, Hamid Reza, Fürtig, Boris, Buck, Janina, Schwalbe, Harald (Prof. Dr.), Noeske, Jonas   +5 more
core   +1 more source

Detection of Guanine and Adenine Using an Aminated Reduced Graphene Oxide Functional Membrane-Modified Glassy Carbon Electrode

Sensors, 2017
A new electrochemical sensor based on a Nafion, aminated reduced graphene oxide and chitosan functional membrane-modified glassy carbon electrode was proposed for the simultaneous detection of adenine and guanine. Fourier transform-infrared spectrometry (
Di Li, Xiao-Lu Yang, Bao-Lin Xiao, Fang-Yong Geng, Jun Hong, Nader Sheibani, Ali Akbar Moosavi-Movahedi   +6 more
doaj   +1 more source

Molecular Self-Assembly of an Unusual Dinuclear Ruthenium(III) Complex Based on the Nucleobase Guanine

Crystals, 2022
The study of crystal structures based on complexes containing purine nucleobases is a significant research subject, mainly regarding the diagnosis and treatment of some diseases and the investigation of genetic mutations and biochemical structures in ...
Marta Orts-Arroyo, Adriana Silvestre-Llora, Isabel Castro, José Martínez-Lillo   +3 more
doaj   +1 more source