Results 81 to 90 of about 201,610 (282)

Guanine quadruplex structures localize to heterochromatin

Nucleic Acids Research, 2015
Increasing amounts of data support a role for guanine quadruplex (G4) DNA and RNA structures in various cellular processes. We stained different organisms with monoclonal antibody 1H6 specific for G4 DNA.
R. Hoffmann, Y. Moshkin, Stijn Mouton, Nicola A. Grzeschik, R. Kalicharan, J. Kuipers, A. Wolters, Kazuki Nishida, A. V. Romashchenko, J. Postberg, H. Lipps, Eugene Berezikov, O. Sibon, B. Giepmans, P. Lansdorp   +14 more
semanticscholar   +1 more source

Guanin im Schweineharn [PDF]

Justus Liebigs Annalen der Chemie, 1876
n ...
openaire   +2 more sources

Anhydrous guanine: a synchrotron study [PDF]

Acta Crystallographica Section C Crystal Structure Communications, 2006
Very small crystals of anhydrous guanine (systematic name: 2-amino-1,7-dihydro-6H-purin-6-one), C5H5N5O, were obtained from an attempted solvothermal synthesis of a potassium complex. Data were collected at 120 K using a synchrotron radiation source. There is one essentially planar mol­ecule in the asymmetric unit.
Guille K, Clegg W
openaire   +4 more sources

An optimized protocol to detect high‐throughput DNA methylation from custom targeted sequences on 96 samples simultaneously

FEBS Open Bio, EarlyView.
Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli, Sophie Valière, Julien Sarry, Cécile Donnadieu, Julie Demars   +4 more
wiley   +1 more source

Synthesis and Spectral Study of New Guanine Derivative (N-((6-Oxo-6,9-Dihydro-1H-Purin-2-yl)Carbamothioyl)Propionamide) and its Complexes with Some Metals Ion

Ibn Al-Haitham Journal for Pure and Applied Sciences
This study included the preparation and characterization of the new guanine derivative (N-((6-oxo-6,9-dihydro-1H-purin-2-yl)carbamothioyl)propionamide), with an exciting chemical structure.
Abdullah Sh. Abdullah Alani, Basima Muhsen Sarhan, Vishwa Deepak Tripathi   +2 more
doaj   +1 more source

Functional Characterization and Pathogenicity Classification of PRRT2 Splice Variants in PRRT2‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Paroxysmal kinesigenic dyskinesia (PKD) is the most common hereditary paroxysmal movement disorder. The PRRT2 gene is the first identified causative gene and accounts for the majority of PKD. In this study, we investigated the pathogenicity of PRRT2 variants in the splice regions. Methods Patients with clinically suspected PKD and no
Jiao‐Jiao Xu, Yu‐Lan Chen, Wan‐Bing Sun, Hong‐Fu Li, Zhi‐Ying Wu, Dian‐Fu Chen   +5 more
wiley   +1 more source

QM-CSA: A Novel Quantum Mechanics-Based Protocol for Evaluation of the Carcinogen-Scavenging Activity of Polyphenolic Compounds

Foods
In this study, a novel quantum mechanics-based protocol for the evaluation of carcinogen-scavenging activity (QM-CSA) is developed. The QM-CSA protocol represents a universal and quantitative approach to evaluate and compare the activation-free energies ...
Veronika Furlan, Jelena Tošović, Urban Bren   +2 more
doaj   +1 more source

Direct determination of guanine in Aciclovir Dispersible Tablets solution by acylpyrazolone modified glassy carbon electrode

Reviews in Analytical Chemistry, 2011
In this article, the investigation of electrochemical determination of guanine(GU) by 1-phenyl-3-methyl-4-(2-furoyl)-5-pyrazolone (HPMαFP) modified glassy carbon electrode (HPMαFP/GCE) in Aciclovir Dispersible Tablets solution was reported.
Li Xueli, Li Jinzhou
doaj   +1 more source

Insights into the biological functions of Dock family guanine nucleotide exchange factors

Genes & Development, 2014
Rho GTPases regulate many essential processes during development, yet the full impact of their upstream regulation through guanine nucleotide exchange factors (GEFs) is only beginning to be appreciated.
M. Laurin, J. Côté
semanticscholar   +1 more source

Real-Time Monitoring of Human Guanine Deaminase Activity by an Emissive Guanine Analog

ACS Chemical Biology, 2021
Guanine deaminase (GDA) deaminates guanine to xanthine. Despite its significance, the study of human GDA remains limited compared to other metabolic deaminases. As a result, its substrate and inhibitor repertoire are limited, and effective real-time activity, inhibitory, and discovery assays are missing.
Bucardo M. S., Wu Y., Ludford P. T., Li Y., Fin A., Tor Y.   +5 more
openaire   +5 more sources